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    GER2 NAD(P)-binding Rossmann-fold superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838368, updated on 15-Feb-2024

    Summary

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    Gene symbol
    GER2
    Gene description
    NAD(P)-binding Rossmann-fold superfamily protein
    Primary source
    Araport:AT1G17890
    Locus tag
    AT1G17890
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F2H15.12; F2H15_12
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (6154264..6155804, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ethylene-dependent gravitropism-deficient and yellow-green-like 3 Neighboring gene ncRNA Neighboring gene basic transcription factor 3 Neighboring gene pseudo Neighboring gene Wall-associated kinase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157
    2. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    3. Multi-omics network-based functional annotation of unknown Arabidopsis genes. Depuydt T, et al. Plant J, 2021 Nov. PMID 34562334
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_101652.3
    NM_202124.2
    NM_202125.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GDP-L-fucose synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in 'de novo' GDP-L-fucose biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    NAD(P)-binding Rossmann-fold superfamily protein
    NP_564040.1
    • GER2; FUNCTIONS IN: coenzyme binding, binding, catalytic activity; INVOLVED IN: GDP-L-fucose biosynthetic process, cellular metabolic process, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: GDP-4-keto-6-deoxymannose-3,5-epimerase-4-reductase 1 (TAIR:AT1G73250.1); Has 26865 Blast hits to 26861 proteins in 2796 species: Archae - 647; Bacteria - 15991; Metazoa - 493; Fungi - 205; Plants - 723; Viruses - 26; Other Eukaryotes - 8780 (source: NCBI BLink).
    NP_973853.1
    • GER2; FUNCTIONS IN: coenzyme binding, binding, catalytic activity; INVOLVED IN: GDP-L-fucose biosynthetic process, cellular metabolic process, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: GDP-4-keto-6-deoxymannose-3,5-epimerase-4-reductase 1 (TAIR:AT1G73250.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_973854.1
    • GER2; FUNCTIONS IN: coenzyme binding, binding, catalytic activity; INVOLVED IN: GDP-L-fucose biosynthetic process, cellular metabolic process, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: GDP-4-keto-6-deoxymannose-3,5-epimerase-4-reductase 1 (TAIR:AT1G73250.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6154264..6155804 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101652.3 → NP_564040.1  NAD(P)-binding Rossmann-fold superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564040.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3EDA2, Q3EDA3, Q9LMU0
      UniProtKB/TrEMBL
      A0A5S9V055
      Conserved Domains (1) summary
      PLN02725
      Location:23 → 328
      PLN02725; GDP-4-keto-6-deoxymannose-3,5-epimerase-4-reductase

    2. NM_202125.3 → NP_973854.1  NAD(P)-binding Rossmann-fold superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973854.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654EBU7, B9DH36
      Conserved Domains (2) summary
      PLN02725
      Location:15 → 320
      PLN02725; GDP-4-keto-6-deoxymannose-3,5-epimerase-4-reductase
      pfam01370
      Location:14 → 245
      Epimerase; NAD dependent epimerase/dehydratase family

    3. NM_202124.2 → NP_973853.1  NAD(P)-binding Rossmann-fold superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973853.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654EBU7, B9DH36
      Conserved Domains (2) summary
      PLN02725
      Location:15 → 320
      PLN02725; GDP-4-keto-6-deoxymannose-3,5-epimerase-4-reductase
      pfam01370
      Location:14 → 245
      Epimerase; NAD dependent epimerase/dehydratase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LMU0.1

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