GID1C alpha/beta-Hydrolases superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Gene symbol: GID1C
Gene description: alpha/beta-Hydrolases superfamily protein
Primary source: Araport:AT5G27320
Locus tag: AT5G27320
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATGID1C; F21A20.30; F21A20_30; GA INSENSITIVE DWARF1C
Summary: Encodes a gibberellin (GA) receptor ortholog of the rice GA receptor gene (OsGID1). Has GA-binding activity, showing higher affinity to GA4. Interacts with DELLA proteins in vivo in the presence of GA4.
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Genomic context

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Location:: chromosome: 5

Exon count:: 2

Sequence:: Chromosome: 5; NC_003076.8 (9628990..9631291)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Partial after-ripening resulted in increased GID1b, but not GID1a or GID1c mRNA levels.
Title: Loss of Arabidopsis thaliana Seed Dormancy is Associated with Increased Accumulation of the GID1 GA Hormone Receptors.
The stronger role of GID1b in non-proteolytic gibberellic acid signaling may result from the fact that GID1b has higher affinity for DELLA protein than GID1a and GID1c.
Title: The roles of the GA receptors GID1a, GID1b, and GID1c in sly1-independent GA signaling.
GID1A plays a major role during fruit-set, whereas GID1B and GID1C have partially redundant function with GID1A in seed development and pod elongation, respectively.
Title: Role of the gibberellin receptors GID1 during fruit-set in Arabidopsis.
GID1A, GID1B and GID1C play distinct roles during seed germination.
Title: Members of the gibberellin receptor gene family GID1 (GIBBERELLIN INSENSITIVE DWARF1) play distinct roles during Lepidium sativum and Arabidopsis thaliana seed germination.
DELLA degradation causing GA responses requires GA biosynthesis, three functionally redundant GA receptors GIBBERELLIN INSENSITIVE DWARF1 (GID1a, b, and c), and the SLEEPY1 (SLY1) F-box subunit of an SCF E3 ubiquitin ligase.
Title: Proteolysis-independent downregulation of DELLA repression in Arabidopsis by the gibberellin receptor GIBBERELLIN INSENSITIVE DWARF1.
The double knockout mutant atgid1a atgid1c showed a dwarf phenotype. The triple knockout mutant atgid1a atgid1b atgid1c did not germinate voluntarily, and only started to grow when the seed coat was peeled off after soaking.
Title: Multiple loss-of-function of Arabidopsis gibberellin receptor AtGID1s completely shuts down a gibberellin signal.
GID1a, GID1b, GID1c are the predominant GA receptors in regulating GA growth response in Arabidopsis. GA binding to GID1a promotes its interaction with DELLA proteins. [GID1c]
Title: Genetic characterization and functional analysis of the GID1 gibberellin receptors in Arabidopsis.
AtGID1a, AtGID1b and AtGID1c function as GA receptors in Arabidopsis. [AtGID1c]
Title: Identification and characterization of Arabidopsis gibberellin receptors.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_122614.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within floral organ morphogenesis	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within gibberellin mediated signaling pathway	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within positive regulation of gibberellic acid mediated signaling pathway	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within raffinose family oligosaccharide biosynthetic process	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within response to gibberellin	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: alpha/beta-Hydrolases superfamily protein

NP_198084.1

GA INSENSITIVE DWARF1C (GID1C); FUNCTIONS IN: hydrolase activity; INVOLVED IN: floral organ morphogenesis, raffinose family oligosaccharide biosynthetic process, positive regulation of gibberellic acid mediated signaling pathway, response to gibberellin stimulus, gibberellin mediated signaling pathway; LOCATED IN: cellular_component unknown; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Lipase, GDXG, active site (InterPro:IPR002168), Alpha/beta hydrolase fold-3 (InterPro:IPR013094); BEST Arabidopsis thaliana protein match is: alpha/beta-Hydrolases superfamily protein (TAIR:AT3G05120.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

9628990..9631291

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_122614.4 → NP_198084.1 alpha/beta-Hydrolases superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_198084.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q940G6

UniProtKB/TrEMBL

A0A178UKX0, A0A5S9Y859, A0A7G2FBM4

Conserved Domains (1) summary

pfam07859
Location:107 → 320

Abhydrolase_3; alpha/beta hydrolase fold