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    CAT5 cationic amino acid transporter 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818060, updated on 15-Oct-2023

    Summary

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    Gene symbol
    CAT5
    Gene description
    cationic amino acid transporter 5
    Primary source
    Araport:AT2G34960
    Locus tag
    AT2G34960
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    cationic amino acid transporter 5; F19I3.19; F19I3_19
    Summary
    Encodes a member of the cationic amino acid transporter (CAT) subfamily of amino acid polyamine choline transporters. Mediates efficient uptake of Lys, Arg and Glu in a yeast system. Localized to the plasma membrane.
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (14743997..14746124, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene VACUOLAR SORTING RECEPTOR 5 Neighboring gene tRNA-Thr Neighboring gene Trimeric LpxA-like enzyme Neighboring gene phosphatidylinositolglycan synthase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular and functional characterization of a family of amino acid transporters from Arabidopsis. Su YH, et al. Plant Physiol, 2004 Oct. PMID 15377779, Free PMC Article
    2. Uncovering Arabidopsis membrane protein interactome enriched in transporters using mating-based split ubiquitin assays and classification models. Chen J, et al. Front Plant Sci, 2012. PMID 22737156, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_129048.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables L-glutamate transmembrane transporter activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables L-lysine transmembrane transporter activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables basic amino acid transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within L-arginine import across plasma membrane IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cationic amino acid transporter 5
    NP_181041.1
    • cationic amino acid transporter 5 (CAT5); CONTAINS InterPro DOMAIN/s: Cationic amino acid transporter (InterPro:IPR015606), Amino acid/polyamine transporter I (InterPro:IPR002293), Amino acid permease domain (InterPro:IPR004841); BEST Arabidopsis thaliana protein match is: cationic amino acid transporter 8 (TAIR:AT1G17120.1); Has 31271 Blast hits to 31152 proteins in 2294 species: Archae - 542; Bacteria - 25908; Metazoa - 1864; Fungi - 1511; Plants - 392; Viruses - 1; Other Eukaryotes - 1053 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      14743997..14746124 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129048.3 → NP_181041.1  cationic amino acid transporter 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181041.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O64759, Q8RX58
      UniProtKB/TrEMBL
      A0A178VPZ9, A0A5S9X409, A0A7G2EBD1
      Conserved Domains (1) summary
      TIGR00906
      Location:54 → 559
      2A0303; cationic amino acid transport permease
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O64759.1

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