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    eps8.L epidermal growth factor receptor pathway substrate 8 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 414529, updated on 11-Apr-2024

    Summary

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    Official Symbol
    eps8.L
    Official Full Name
    epidermal growth factor receptor pathway substrate 8 L homeolog
    Primary source
    Xenbase:XB-GENE-996941
    Locus tag
    XELAEV_18016574mg
    See related
    EnsemblRapid:ENSXLAG00005005735
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    eps8
    Annotation information
    Annotation category: partial on reference assembly
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    Genomic context

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    Location:
    chromosome: 3L
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (168585..208921, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (165248..205987, complement)

    Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene RAS like estrogen regulated growth inhibitor L homeolog Neighboring gene protein tyrosine phosphatase, receptor type O L homeolog Neighboring gene serine/threonine kinase receptor associated protein L homeolog Neighboring gene solute carrier family 15, member 5 L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC81285

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within positive regulation of ruffle assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ruffle membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    epidermal growth factor receptor pathway substrate 8 L homeolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001091108.1 → NP_001084577.1  epidermal growth factor receptor pathway substrate 8 L homeolog

      See identical proteins and their annotated locations for NP_001084577.1

      Status: PROVISIONAL

      Source sequence(s)
      BC068768
      UniProtKB/TrEMBL
      A0A974DBM5, Q6NU33
      Related
      ENSXLAP00005017105.1, ENSXLAT00005017393.1
      Conserved Domains (3) summary
      cd09540
      Location:685 → 749
      SAM_EPS8-like; SAM domain of EPS8-like subfamily
      cd11764
      Location:496 → 549
      SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
      cd01210
      Location:58 → 188
      PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      168585..208921 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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