U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

dusB tRNA-dihydrouridine synthase B [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947707, updated on 19-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
dusB
Official Full Name
tRNA-dihydrouridine synthase B
Primary source
ECOCYC:EG11311
Locus tag
b3260
See related
ASAP:ABE-0010700
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3247; yhdG
Summary
DusB and DusC together account for about half of the 5,6-dihydrouridine modification observed in wild-type cellular tRNA, and DusA accounts for the other half . [More information is available at EcoCyc: EG11311].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (3410280..3411245)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF997 domain-containing protein YhdT Neighboring gene pantothenate:Na(+) symporter Neighboring gene ribosomal protein L11 methyltransferase Neighboring gene DNA-binding transcriptional dual regulator Fis Neighboring gene DNA adenine methyltransferase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Unveiling structural and functional divergences of bacterial tRNA dihydrouridine synthases: perspectives on the evolution scenario. Bou-Nader C, et al. Nucleic Acids Res, 2018 Feb 16. PMID 29294097, Free PMC Article
  2. Escherichia coli host factor for site-specific DNA inversion: cloning and characterization of the fis gene. Koch C, et al. Proc Natl Acad Sci U S A, 1988 Jun. PMID 2837762, Free PMC Article
  3. The E.coli fis promoter is subject to stringent control and autoregulation. Ninnemann O, et al. EMBO J, 1992 Mar. PMID 1547773, Free PMC Article
  4. Identification of the tRNA-dihydrouridine synthase family. Bishop AC, et al. J Biol Chem, 2002 Jul 12. PMID 11983710
  5. Isolation of the gene encoding the Hin recombinational enhancer binding protein. Johnson RC, et al. Proc Natl Acad Sci U S A, 1988 May. PMID 2835774, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The complete substrate specificities of the three Escherichia coli Dus tRNA-dihydrouridine synthases have been described, and the crystal structure of DusB has been solved.
    Title: Unveiling structural and functional divergences of bacterial tRNA dihydrouridine synthases: perspectives on the evolution scenario.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables FMN binding IEA
Inferred from Electronic Annotation
more info
  
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables tRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables tRNA dihydrouridine synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables tRNA dihydrouridine synthase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within response to radiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in tRNA dihydrouridine synthesis IEA
Inferred from Electronic Annotation
more info
  
involved_in tRNA processing IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
tRNA-dihydrouridine synthase B

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3410280..3411245
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417726.1 tRNA-dihydrouridine synthase B [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417726.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9ANH0
    Conserved Domains (1) summary
    PRK10415
    Location:1 → 321
    PRK10415; tRNA-dihydrouridine synthase B; Provisional
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.