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scoC transcriptional regulator of extracellular protease production, sporulation and bacilysin production (MarR family) [ Bacillus subtilis subsp. subtilis str. 168 ]

Gene ID: 939765, updated on 6-Jun-2024

Summary

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Gene symbol
scoC
Gene description
transcriptional regulator of extracellular protease production, sporulation and bacilysin production (MarR family)
Locus tag
BSU_09990
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
Lineage
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
Old locus tag
BSU09990
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Genomic context

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Sequence:
NC_000964.3 (1073106..1073717, complement)

NC_000964.3Genomic Context describing neighboring genes Neighboring gene spore and germination protein Neighboring gene putative membrane enzyme Neighboring gene hypothetical protein Neighboring gene putative membrane protein; acid tolerance protein Neighboring gene membrane protein of unknown function

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000964.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A dual mode of regulation of flgM by ScoC in Bacillus subtilis. Kodgire P, et al. Can J Microbiol, 2009 Aug. PMID 19898538
  2. Transcriptional activator YesS is stimulated by histidine-phosphorylated HPr of the Bacillus subtilis phosphotransferase system. Poncet S, et al. J Biol Chem, 2009 Oct 9. PMID 19651770, Free PMC Article
  3. hag expression in Bacillus subtilis is both negatively and positively regulated by ScoC. Kodgire P, et al. Microbiology (Reading), 2009 Jan. PMID 19118355
  4. Characterization of a mannose utilization system in Bacillus subtilis. Sun T, et al. J Bacteriol, 2010 Apr. PMID 20139185, Free PMC Article
  5. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The phosphoenolpyruvate (PEP)-dependent phosphorylation by the histidine protein HPr via His15 plays an essential role in transcriptional activation of P(manP) and P(manR).
    Title: Characterization of a mannose utilization system in Bacillus subtilis.
  2. results clearly suggest that the transition state regulator ScoC downregulates FlgM and thereby increases the availability of sigmaD by specifically binding to two sites in the promoter region of the flgM operon.
    Title: A dual mode of regulation of flgM by ScoC in Bacillus subtilis.
  3. Results suggest that YesS interacts with HPr and His(P)-HPr but not with Ser(P)-HPr.
    Title: Transcriptional activator YesS is stimulated by histidine-phosphorylated HPr of the Bacillus subtilis phosphotransferase system.
  4. ScoC negatively regulates hag, by binding to its promoter, and positively regulates hag by increasing the availability of sigma(D) by downregulating the levels of the anti-sigma(D)-factor FlgM.
    Title: hag expression in Bacillus subtilis is both negatively and positively regulated by ScoC.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
transcriptional regulator of extracellular protease production, sporulation and bacilysin production (MarR family)
NP_388880.1
  • Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14629015, 15126467, 16321961, 16923912, 19801406, 20382764, 23660663, 25966844, 26473603, 26728191, 22720735; Product type r : regulator

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000964.3 Reference assembly

    Range
    1073106..1073717 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_388880.1 transcriptional regulator of extracellular protease production, sporulation and bacilysin production (MarR family) [Bacillus subtilis subsp. subtilis str. 168]

    See identical proteins and their annotated locations for NP_388880.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    D4G742
    Conserved Domains (1) summary
    PRK13777
    Location:2 → 185
    PRK13777; HTH-type transcriptional regulator Hpr
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P11065.1

Gene LinkOut

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Other Literature Sources
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Research Materials