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cpsf3 DNA repair metallo-beta-lactamase domain-containing protein [ Dictyostelium discoideum AX4 ]

Gene ID: 8619353, updated on 17-May-2024

Summary

Gene symbol
cpsf3
Gene description
DNA repair metallo-beta-lactamase domain-containing protein
Primary source
dictyBase:DDB_G0274799
Locus tag
DDB_G0274799
See related
AmoebaDB:DDB_G0274799; VEuPathDB:DDB_G0274799
Gene type
protein coding
RNA name
beta-lactamase domain-containing protein
RefSeq status
PROVISIONAL
Organism
Dictyostelium discoideum AX4 (strain: AX4)
Lineage
Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Dictyostelium
Old locus tag
DDBDRAFT_0217481; DDBDRAFT_0233696; DDB_0217481; DDB_0233696
NEW
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Try the new Transcript table

Genomic context

Location:
chromosome: 2
Exon count:
2
Sequence:
Chromosome: 2; NC_007088.5 (3904161..3906570, complement)

Chromosome 2 - NC_007088.5Genomic Context describing neighboring genes Neighboring gene 3-ketoacyl-CoA thiolase Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Pathways from PubChem

General gene information

Gene Ontology Provided by dictyBase

Function Evidence Code Pubs
enables 5'-3' RNA exonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA endonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables endonuclease activity IEA
Inferred from Electronic Annotation
more info
 
enables mRNA 3'-UTR AU-rich region binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in mRNA 3'-end processing by stem-loop binding and cleavage IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of mRNA cleavage and polyadenylation specificity factor complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mRNA cleavage and polyadenylation specificity factor complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Names
DNA repair metallo-beta-lactamase domain-containing protein
beta-lactamase domain-containing protein
cleavage and polyadenylation specificity factor 73 kDa subunit

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_007088.5 Reference assembly

    Range
    3904161..3906570 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_638834.1XP_643926.1  beta-lactamase domain-containing protein [Dictyostelium discoideum AX4]

    See identical proteins and their annotated locations for XP_643926.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q555Y4, Q86A79
    Conserved Domains (5) summary
    smart01027
    Location:273394
    Beta-Casp; Beta-Casp domain
    smart01098
    Location:499751
    CPSF73-100_C; This is the C-terminal conserved region of the pre-mRNA 3'-end-processing of the polyadenylation factor CPSF-73/CPSF-100 proteins
    COG1236
    Location:36472
    YSH1; RNA processing exonuclease, beta-lactamase fold, Cft2 family [Translation, ribosomal structure and biogenesis]
    pfam07521
    Location:409447
    RMMBL; RNA-metabolizing metallo-beta-lactamase
    cd16292
    Location:36232
    CPSF3-like_MBL-fold; cleavage and polyadenylation specificity factor (CPSF) subunit 3 and related proteins; MBL-fold metallo-hydrolase domain