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MBR1 Mbr1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853769, updated on 18-Sep-2024

Summary

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Official Symbol
MBR1
Official Full Name
Mbr1p
Primary source
SGD:S000001576
Locus tag
YKL093W
See related
AllianceGenome:SGD:S000001576; FungiDB:YKL093W; VEuPathDB:YKL093W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in aerobic respiration. Predicted to be located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (264789..265808)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene mRNA splicing protein YJU2 Neighboring gene acylglycerol lipase Neighboring gene GTPase-activating protein BUD2 Neighboring gene phosphatidylinositol/phosphatidylcholine-binding protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001143.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of nuclear genes which participate to mitochondrial translation in Saccharomyces cerevisiae. Valens M, et al. Biochimie, 1991 Dec. PMID 1725263
  2. The MBR1 gene from Saccharomyces cerevisiae is activated by and required for growth under sub-optimal conditions. Reisdorf P, et al. Mol Gen Genet, 1997 Jul. PMID 9267436
  3. MBR1 and MBR3, two related yeast genes that can suppress the growth defect of hap2, hap3 and hap4 mutants. Daignan-Fornier B, et al. Mol Gen Genet, 1994 Jun 3. PMID 8208248
  4. Strand-specific RNA sequencing reveals extensive regulated long antisense transcripts that are conserved across yeast species. Yassour M, et al. Genome Biol, 2010. PMID 20796282, Free PMC Article
  5. The protein factor-arrest 11 (Far11) is essential for the toxicity of human caspase-10 in yeast and participates in the regulation of autophagy and the DNA damage signaling. Lisa-Santamaría P, et al. J Biol Chem, 2012 Aug 24. PMID 22782902, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in aerobic respiration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Mbr1p
NP_012830.1
  • Protein involved in mitochondrial functions and stress response; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; MBR1 has a paralog, ISF1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    264789..265808
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179659.1 → NP_012830.1  TPA: Mbr1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012830.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    C8ZC82, D6VXJ5, P23493, Q2VQW7
    UniProtKB/TrEMBL
    G2WHU0, N1NZ45
    Conserved Domains (1) summary
    pfam17058
    Location:29 → 248
    MBR1; Mitochondrial biogenesis regulation protein 1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P23493.2

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