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TDH3 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3 [ Saccharomyces cerevisiae S288c ]

Gene ID: 853106, updated on 7-Sep-2014
Gene symbol
TDH3
Gene description
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3
Primary source
SGD:S000003424
Locus tag
YGR192C
Gene type
protein coding
RNA name
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
GLD1; HSP35; HSP36; SSS2
See TDH3 in MapViewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (882812..883810, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene tRNA Neighboring gene histidine permease Neighboring gene Pdx1p Neighboring gene xylulokinase

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
NAD binding IEA
Inferred from Electronic Annotation
more info
 
NADP binding IEA
Inferred from Electronic Annotation
more info
 
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity IDA
Inferred from Direct Assay
more info
PubMed 
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
gluconeogenesis IEP
Inferred from Expression Pattern
more info
PubMed 
glucose metabolic process IEA
Inferred from Electronic Annotation
more info
 
glycolytic process IEA
Inferred from Electronic Annotation
more info
 
glycolytic process IEP
Inferred from Expression Pattern
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
reactive oxygen species metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
fungal-type cell wall IDA
Inferred from Direct Assay
more info
PubMed 
lipid particle IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IPI
Inferred from Physical Interaction
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
Names
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3
NP_011708.3
  • Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3; involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell wall; GAPDH-derived antimicrobial peptides secreted by S. cerevisiae are active against a wide variety of wine-related yeasts and bateria; TDH3 has a paralog, TDH2, that arose from the whole genome duplication

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 

    Range
    882812..883810
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181321.3NP_011708.3  glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3 [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_011708.3

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P00359
    Conserved Domains (3) summary
    COG0057
    Location:1332
    Blast Score: 1367
    GapA; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]
    pfam00044
    Location:2150
    Blast Score: 626
    Gp_dh_N; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
    pfam02800
    Location:155312
    Blast Score: 727
    Gp_dh_C; Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain