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BBD1 bifunctional nuclease in basal defense response 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 843874, updated on 18-Sep-2024

Summary

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Official Symbol
BBD1
Official Full Name
bifunctional nuclease in basal defense response 1
Primary source
TAIR:AT1G75380
Locus tag
AT1G75380
See related
Araport:AT1G75380
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATBBD1; bifunctional nuclease in basal defense response 1; F1B16.9; F1B16_9
Summary
Encodes a nuclease involved in ABA-mediated callose deposition. It has been shown to interact with JAZ proteins, binds to a jasmonic acid-responsive element (JARE) and repress AtJMT expression.
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Genomic context

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Location:
chromosome: 1
Exon count:
11
Sequence:
Chromosome: 1; NC_003070.9 (28281195..28284168, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Zinc finger C-x8-C-x5-C-x3-H type family protein Neighboring gene Ribosomal protein L31 Neighboring gene uncharacterized protein Neighboring gene Sec14p-like phosphatidylinositol transfer family protein Neighboring gene ncRNA Neighboring gene basic leucine-zipper 44

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Overexpression of AtBBD1, Arabidopsis Bifunctional Nuclease, Confers Drought Tolerance by Enhancing the Expression of Regulatory Genes in ABA-Mediated Drought Stress Signaling. Huque AKMM, et al. Int J Mol Sci, 2021 Mar 13. PMID 33805821, Free PMC Article
  2. Phylogenetic Analysis and In Vitro Bifunctional Nuclease Assay of Arabidopsis BBD1 and BBD2. Huque AKMM, et al. Molecules, 2020 May 6. PMID 32384799, Free PMC Article
  3. Novel bifunctional nucleases, OmBBD and AtBBD1, are involved in abscisic acid-mediated callose deposition in Arabidopsis. You MK, et al. Plant Physiol, 2010 Feb. PMID 20018603, Free PMC Article
  4. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
  5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Overexpression of AtBBD1, Arabidopsis Bifunctional Nuclease, Confers Drought Tolerance by Enhancing the Expression of Regulatory Genes in ABA-Mediated Drought Stress Signaling.
    Title: Overexpression of AtBBD1, Arabidopsis Bifunctional Nuclease, Confers Drought Tolerance by Enhancing the Expression of Regulatory Genes in ABA-Mediated Drought Stress Signaling.
  2. Phylogenetic Analysis and In Vitro Bifunctional Nuclease Assay of Arabidopsis BBD1 and BBD2.
    Title: Phylogenetic Analysis and In Vitro Bifunctional Nuclease Assay of Arabidopsis BBD1 and BBD2.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_106192.3
NM_179559.3
NM_179560.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables RNA nuclease activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables deoxyribonuclease I activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables nuclease activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within abscisic acid-activated signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within defense response to fungus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of stomatal movement IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to water deprivation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
bifunctional nuclease in basal defense response 1
NP_177671.1
  • bifunctional nuclease in basal defense response 1 (BBD1); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF151 (InterPro:IPR003729), UvrB/UvrC protein (InterPro:IPR001943); BEST Arabidopsis thaliana protein match is: Wound-responsive family protein (TAIR:AT1G19660.2); Has 843 Blast hits to 843 proteins in 291 species: Archae - 44; Bacteria - 501; Metazoa - 0; Fungi - 0; Plants - 105; Viruses - 0; Other Eukaryotes - 193 (source: NCBI BLink).
NP_849890.1
  • bifunctional nuclease in basal defense response 1 (BBD1); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF151 (InterPro:IPR003729), UvrB/UvrC protein (InterPro:IPR001943); BEST Arabidopsis thaliana protein match is: Wound-responsive family protein (TAIR:AT1G19660.2); Has 843 Blast hits to 843 proteins in 291 species: Archae - 44; Bacteria - 501; Metazoa - 0; Fungi - 0; Plants - 105; Viruses - 0; Other Eukaryotes - 193 (source: NCBI BLink).
NP_849891.1
  • bifunctional nuclease in basal defense response 1 (BBD1); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF151 (InterPro:IPR003729), UvrB/UvrC protein (InterPro:IPR001943); BEST Arabidopsis thaliana protein match is: Wound-responsive family protein (TAIR:AT1G19660.2); Has 843 Blast hits to 843 proteins in 291 species: Archae - 44; Bacteria - 501; Metazoa - 0; Fungi - 0; Plants - 105; Viruses - 0; Other Eukaryotes - 193 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    28281195..28284168 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001334685.1 → NP_001322708.1  bifunctional nuclease in basal defense response 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FWS6
    UniProtKB/TrEMBL
    A0A178WDF6, A0A5S9WUN5
    Conserved Domains (2) summary
    pfam02151
    Location:291 → 318
    UVR; UvrB/uvrC motif
    cl00553
    Location:136 → 241
    DNase-RNase; Bifunctional nuclease

  2. NM_179559.3 → NP_849890.1  bifunctional nuclease in basal defense response 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849890.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FWS6
    UniProtKB/TrEMBL
    A0A178WDF6, A0A5S9WUN5
    Conserved Domains (2) summary
    pfam02151
    Location:291 → 318
    UVR; UvrB/uvrC motif
    cl00553
    Location:136 → 241
    DNase-RNase; Bifunctional nuclease

  3. NM_106192.3 → NP_177671.1  bifunctional nuclease in basal defense response 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_177671.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FWS6
    UniProtKB/TrEMBL
    A0A178WDF6, A0A5S9WUN5
    Conserved Domains (2) summary
    pfam02151
    Location:291 → 318
    UVR; UvrB/uvrC motif
    cl00553
    Location:136 → 241
    DNase-RNase; Bifunctional nuclease

  4. NM_179560.3 → NP_849891.1  bifunctional nuclease in basal defense response 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849891.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FWS6
    UniProtKB/TrEMBL
    A0A178WDF6, A0A5S9WUN5
    Conserved Domains (2) summary
    pfam02151
    Location:291 → 318
    UVR; UvrB/uvrC motif
    cl00553
    Location:136 → 241
    DNase-RNase; Bifunctional nuclease
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FWS6.1

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