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WAVE2 SCAR family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839791, updated on 18-Sep-2024

Summary

Official Symbol
WAVE2
Official Full Name
SCAR family protein
Primary source
TAIR:AT1G29170
Locus tag
AT1G29170
See related
Araport:AT1G29170
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATSCAR3; F28N24.14; F28N24_14; SCAR3; WASP (WISKOTT-ALDRICH SYNDROME PROTEIN)-FAMILY VERPROLIN HOMOLOGOUS PROTEIN 2
Summary
Encodes a member of the SCAR family.These proteins are part of a complex (WAVE) complex.The SCAR subunit activates the ARP2/3 complex which in turn act as a nucleator for actin filaments.
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Genomic context

Location:
chromosome: 1
Exon count:
9
Sequence:
Chromosome: 1; NC_003070.9 (10190137..10195213, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene non-ATPase subunit 9 Neighboring gene Dof-type zinc finger DNA-binding family protein Neighboring gene cysteine/histidine-rich C1 domain protein Neighboring gene Cysteine/Histidine-rich C1 domain family protein Neighboring gene miscRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

NM_001123903.2
NM_001123904.2
NM_102658.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within positive regulation of actin nucleation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of SCAR complex TAS
Traceable Author Statement
more info
PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
 

General protein information

Preferred Names
SCAR family protein
NP_001117375.1
  • WAVE2; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: positive regulation of actin nucleation; LOCATED IN: SCAR complex; BEST Arabidopsis thaliana protein match is: SCAR family protein (TAIR:AT2G34150.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_001117376.1
  • WAVE2; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: positive regulation of actin nucleation; LOCATED IN: SCAR complex; BEST Arabidopsis thaliana protein match is: SCAR family protein (TAIR:AT2G34150.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_174212.2
  • WAVE2; BEST Arabidopsis thaliana protein match is: SCAR family protein (TAIR:AT2G34150.2); Has 1242 Blast hits to 945 proteins in 214 species: Archae - 0; Bacteria - 272; Metazoa - 455; Fungi - 71; Plants - 226; Viruses - 5; Other Eukaryotes - 213 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    10190137..10195213 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_102658.3NP_174212.2  SCAR family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_174212.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9LP46
    UniProtKB/TrEMBL
    A0A178WGL1, A0A5S9WC29
  2. NM_001123903.2NP_001117375.1  SCAR family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001117375.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9WC29, B3H7L7
  3. NM_001123904.2NP_001117376.1  SCAR family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001117376.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9WC29, B3H466