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PPa1 pyrophosphorylase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839579, updated on 18-Sep-2024

Summary

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Official Symbol
PPa1
Official Full Name
pyrophosphorylase 1
Primary source
TAIR:AT1G01050
Locus tag
AT1G01050
See related
Araport:AT1G01050
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtPPa1; pyrophosphorylase 1; T25K16.5; T25K16_5
Summary
Encodes a soluble protein with inorganic pyrophosphatase activity that is highly specific for Mg-inorganic pyrophosphate.
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Genomic context

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Location:
chromosome: 1
Exon count:
10
Sequence:
Chromosome: 1; NC_003070.9 (31170..33171, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene dicer-like 1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Homeodomain-like superfamily protein Neighboring gene nodulin MtN21 /EamA-like transporter family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Oil and protein accumulation in developing seeds is influenced by the expression of a cytosolic pyrophosphatase in Arabidopsis. Meyer K, et al. Plant Physiol, 2012 Jul. PMID 22566496, Free PMC Article
  2. Crystal structures of plant inorganic pyrophosphatase, an enzyme with a moonlighting autoproteolytic activity. Grzechowiak M, et al. Biochem J, 2019 Aug 22. PMID 31371393
  3. Vacuolar H(+)-Pyrophosphatase and Cytosolic Soluble Pyrophosphatases Cooperatively Regulate Pyrophosphate Levels in Arabidopsis thaliana. Segami S, et al. Plant Cell, 2018 May. PMID 29691313, Free PMC Article
  4. Virus-induced gene silencing of plastidial soluble inorganic pyrophosphatase impairs essential leaf anabolic pathways and reduces drought stress tolerance in Nicotiana benthamiana. George GM, et al. Plant Physiol, 2010 Sep. PMID 20605913, Free PMC Article
  5. High-throughput protein localization in Arabidopsis using Agrobacterium-mediated transient expression of GFP-ORF fusions. Koroleva OA, et al. Plant J, 2005 Jan. PMID 15610358

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Crystal structures of plant inorganic pyrophosphatase, an enzyme with a moonlighting autoproteolytic activity.
    Title: Crystal structures of plant inorganic pyrophosphatase, an enzyme with a moonlighting autoproteolytic activity.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001331245.1
NM_099987.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables inorganic diphosphate phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables inorganic diphosphate phosphatase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables inorganic diphosphate phosphatase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell wall biogenesis IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within cell wall biogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within lipid storage IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in phosphate-containing compound metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of starch metabolic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within regulation of starch metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within sucrose metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within sucrose metabolic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in cytosol HDA PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus HDA PubMed 

General protein information

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Preferred Names
pyrophosphorylase 1
NP_171613.1
  • pyrophosphorylase 1 (PPa1); FUNCTIONS IN: inorganic diphosphatase activity; INVOLVED IN: phosphate metabolic process, metabolic process; LOCATED IN: nucleus, membrane, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Inorganic pyrophosphatase (InterPro:IPR008162); BEST Arabidopsis thaliana protein match is: pyrophosphorylase 3 (TAIR:AT2G46860.1); Has 5987 Blast hits to 5987 proteins in 1845 species: Archae - 172; Bacteria - 4313; Metazoa - 247; Fungi - 261; Plants - 270; Viruses - 0; Other Eukaryotes - 724 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    31170..33171 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_099987.4 → NP_171613.1  pyrophosphorylase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_171613.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q93V56, Q9MAM9
    UniProtKB/TrEMBL
    A0A178WLC4, A0A5S9XNW6
    Conserved Domains (1) summary
    PLN02373
    Location:25 → 212
    PLN02373; soluble inorganic pyrophosphatase

  2. NM_001331245.1 → NP_001322481.1  pyrophosphorylase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q93V56, Q9MAM9
    UniProtKB/TrEMBL
    A0A178WLC4, A0A5S9XNW6
    Conserved Domains (1) summary
    PLN02373
    Location:25 → 212
    PLN02373; soluble inorganic pyrophosphatase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q93V56.1

Gene LinkOut

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