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STO B-box zinc finger family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837113, updated on 7-Sep-2023

Summary

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Gene symbol
STO
Gene description
B-box zinc finger family protein
Primary source
Araport:AT1G06040
Locus tag
AT1G06040
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
B-box domain protein 24; BBX24; SALT TOLERANCE; T21E18.9; T21E18_9
Summary
Encodes salt tolerance protein (STO) which confers salt tolerance to yeast cells. Fully complements calcineurin deficient yeast but does not encode a phosphoprotein phosphatase. Sequence has similarities to CONSTANS. STO co-localizes with COP1 and plays a role in light signaling.
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Genomic context

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Location:
chromosome: 1
Exon count:
2
Sequence:
Chromosome: 1; NC_003070.9 (1828340..1829983, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene pfkB-like carbohydrate kinase family protein Neighboring gene pfkB-like carbohydrate kinase family protein Neighboring gene uncharacterized protein Neighboring gene ENHANCED DISEASE RESISTANCE-like protein (DUF1336) Neighboring gene LisH and RanBPM domains containing protein Neighboring gene Basic-leucine zipper (bZIP) transcription factor family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Quantitative Proteomic Analyses Identify STO/BBX24 -Related Proteins Induced by UV-B. Lyu G, et al. Int J Mol Sci, 2020 Apr 3. PMID 32260266, Free PMC Article
  2. STO and GA negatively regulate UV-B-induced Arabidopsis root growth inhibition. Lyu G, et al. Plant Signal Behav, 2019. PMID 31595819, Free PMC Article
  3. The B-box family gene STO (BBX24) in Arabidopsis thaliana regulates flowering time in different pathways. Li F, et al. PLoS One, 2014. PMID 24498334, Free PMC Article
  4. Salt tolerance (STO), a stress-related protein, has a major role in light signalling. Indorf M, et al. Plant J, 2007 Aug. PMID 17605755
  5. BBX24 Interacts with JAZ3 to Promote Growth by Reducing DELLA Activity in Shade Avoidance. Saura-Sánchez M, et al. Plant Cell Physiol, 2023 May 15. PMID 36715091

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. BBX24 Interacts with JAZ3 to Promote Growth by Reducing DELLA Activity in Shade Avoidance.
    Title: BBX24 Interacts with JAZ3 to Promote Growth by Reducing DELLA Activity in Shade Avoidance.
  2. Quantitative Proteomic Analyses Identify STO/BBX24 -Related Proteins Induced by UV-B.
    Title: Quantitative Proteomic Analyses Identify STO/BBX24 -Related Proteins Induced by UV-B.
  3. UV-B inhibited the growth of Arabidopsis root, possibly because it changes the Gibberellic acid signal and inhibited cell division and cell elongation, which be related to COP1 and STO genes.
    Title: STO and GA negatively regulate UV-B-induced Arabidopsis root growth inhibition.
  4. Findings indicate that both B-Box Proteins BBX21 and BBX24 regulate ELONGATED HYPOCOTYL 5 protein (HY5) activity post-transcriptionally, in opposite ways.
    Title: Two B-Box Proteins Regulate Photomorphogenesis by Oppositely Modulating HY5 through their Diverse C-Terminal Domains.
  5. BBX24 physically interacts with DELLA proteins and alleviates DELLA-mediated repression of PIF4 activity.[BBX24]
    Title: The transcriptional regulator BBX24 impairs DELLA activity to promote shade avoidance in Arabidopsis thaliana.
  6. Data indicate that the expression of the B-box family gene STO (BBX24) is controlled by circadian rhythm and is affected by environmental factors and phytohormones
    Title: The B-box family gene STO (BBX24) in Arabidopsis thaliana regulates flowering time in different pathways.
  7. BX24 and BBX25 physically interact with HYH which leads to depletion of HYH molecules from the active pool and, thus indirectly, reduce the function of HY5 in promoting photomorphogenesis. [BBX24]
    Title: Molecular interactions of BBX24 and BBX25 with HYH, HY5 HOMOLOG, to modulate Arabidopsis seedling development.
  8. Data suggest that BBX25 (At2g31380) and BBX24 (At1g06040) function as transcriptional corepressors, probably by forming inactive heterodimers with HY5 (At5g11260) downregulating BBX22 (AT1G78600) expression for the light-mediated seedling development.
    Title: The Arabidopsis B-BOX protein BBX25 interacts with HY5, negatively regulating BBX22 expression to suppress seedling photomorphogenesis.
  9. STO/BBX24 functions as a negative regulator of photomorphogenic UV-B responses by interacting with both COP1 and HY5.
    Title: Arabidopsis STO/BBX24 negatively regulates UV-B signaling by interacting with COP1 and repressing HY5 transcriptional activity.
  10. Mutations in the region responsible for the interaction with COP1 revealed that a physical interaction of the proteins is also required for degradation of BBX24 in the light and for normal photomorphogenesis.
    Title: Nuclear localization and interaction with COP1 are required for STO/BBX24 function during photomorphogenesis.
Submit: New GeneRIF Correction See all GeneRIFs (11)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_100484.4
NM_179267.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription coregulator activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within photomorphogenesis IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within photoperiodism, flowering IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within positive regulation of shade avoidance IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within positive regulation of shade avoidance IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within positive regulation of shade avoidance IPI
Inferred from Physical Interaction
more info
 PubMed 
acts_upstream_of_or_within response to light stimulus IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to salt stress IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within seedling development IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within vegetative to reproductive phase transition of meristem IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
B-box zinc finger family protein
NP_172094.1
  • SALT TOLERANCE (STO); CONTAINS InterPro DOMAIN/s: Zinc finger, B-box (InterPro:IPR000315); BEST Arabidopsis thaliana protein match is: salt tolerance homologue (TAIR:AT2G31380.1); Has 1912 Blast hits to 1325 proteins in 114 species: Archae - 0; Bacteria - 0; Metazoa - 5; Fungi - 2; Plants - 1809; Viruses - 0; Other Eukaryotes - 96 (source: NCBI BLink).
NP_849598.1
  • SALT TOLERANCE (STO); CONTAINS InterPro DOMAIN/s: Zinc finger, B-box (InterPro:IPR000315); BEST Arabidopsis thaliana protein match is: salt tolerance homologue (TAIR:AT2G31380.1); Has 1915 Blast hits to 1323 proteins in 114 species: Archae - 0; Bacteria - 0; Metazoa - 5; Fungi - 2; Plants - 1814; Viruses - 0; Other Eukaryotes - 94 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    1828340..1829983 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_100484.4 → NP_172094.1  B-box zinc finger family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_172094.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q96288
    UniProtKB/TrEMBL
    A0A178W110, A0A5S9SVX4, A0A654E7D0
    Conserved Domains (1) summary
    cd19821
    Location:5 → 47
    Bbox1_BBX-like; B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and similar proteins

  2. NM_179267.2 → NP_849598.1  B-box zinc finger family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849598.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4IBY7
    Conserved Domains (1) summary
    smart00336
    Location:55 → 98
    BBOX; B-Box-type zinc finger
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q96288.1

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