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APC2 Mitochondrial substrate carrier family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 835178, updated on 11-Apr-2024

Summary

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Gene symbol
APC2
Gene description
Mitochondrial substrate carrier family protein
Primary source
Araport:AT5G51050
Locus tag
AT5G51050
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATP/phosphate carrier 2; K3K7.23; K3K7_23
Summary
Encodes a mitochondrial ATP-Mg/Pi transporter. Binds to calcium.
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Genomic context

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Location:
chromosome: 5
Exon count:
5
Sequence:
Chromosome: 5; NC_003076.8 (20753040..20756137)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene succinate dehydrogenase assembly factor Neighboring gene tRNA-Ser Neighboring gene NADPH/respiratory burst oxidase protein D

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional characterization and organ distribution of three mitochondrial ATP-Mg/Pi carriers in Arabidopsis thaliana. Monné M, et al. Biochim Biophys Acta, 2015 Oct. PMID 26140942
  2. Mitochondrial ATP-Mg/phosphate carriers transport divalent inorganic cations in complex with ATP. Monné M, et al. J Bioenerg Biomembr, 2017 Oct. PMID 28695448
  3. Arabidopsis calcium-binding mitochondrial carrier proteins as potential facilitators of mitochondrial ATP-import and plastid SAM-import. Stael S, et al. FEBS Lett, 2011 Dec 15. PMID 22062157
  4. Functional definition of outer membrane proteins involved in preprotein import into mitochondria. Lister R, et al. Plant Cell, 2007 Nov. PMID 17981999, Free PMC Article
  5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_124484.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ADP transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables AMP transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ATP transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables calcium ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphate transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within ADP transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within AMP transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within ATP transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within ATP transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within monoatomic anion transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within monoatomic cation transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within nucleotide transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within phosphate ion transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within xenobiotic transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Mitochondrial substrate carrier family protein
NP_199918.2
  • Mitochondrial substrate carrier family protein; FUNCTIONS IN: binding, calcium ion binding; INVOLVED IN: transport, transmembrane transport; LOCATED IN: mitochondrial inner membrane, membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), Mitochondrial substrate carrier (InterPro:IPR001993), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048), Mitochondrial carrier protein (InterPro:IPR002067), EF-HAND 2 (InterPro:IPR018249), Mitochondrial substrate/solute carrier (InterPro:IPR018108); BEST Arabidopsis thaliana protein match is: Mitochondrial substrate carrier family protein (TAIR:AT5G07320.1); Has 35093 Blast hits to 20803 proteins in 1083 species: Archae - 0; Bacteria - 15; Metazoa - 13922; Fungi - 9690; Plants - 7280; Viruses - 2; Other Eukaryotes - 4184 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    20753040..20756137
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_124484.2 → NP_199918.2  Mitochondrial substrate carrier family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UN46, A0A5S9YD71
Nucleotide Protein
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