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ERA1 Prenyltransferase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 834026, updated on 7-Sep-2023

Summary

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Gene symbol
ERA1
Gene description
Prenyltransferase family protein
Primary source
Araport:AT5G40280
Locus tag
AT5G40280
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA FARNESYL TRANSFERASE BETA SUBUNIT; ATFTB; ENHANCED RESPONSE TO ABA 1; FARNESYL TRANSFERASE BETA SUBUNIT; MSN9.180; MSN9_180; WIG; WIGGUM
Summary
encodes a beta subunit of farnesyl-trans-transferase, which is involved in meristem organization and ABA-mediated signal transduction pathway. Mutant phenotypes have been observed in meristem organization, and response to abscisic acid and drought.
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Genomic context

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See ERA1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
14
Sequence:
Chromosome: 5; NC_003076.8 (16101343..16104962)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene HD domain-containing metal-dependent phosphohydrolase family protein Neighboring gene ncRNA Neighboring gene HD domain-containing metal-dependent phosphohydrolase family protein Neighboring gene Uncharacterized protein family (UPF0497)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Role of ENHANCED RESPONSES TO ABA1 (ERA1) in Arabidopsis Stomatal Responses Is Beyond ABA Signaling. Jalakas P, et al. Plant Physiol, 2017 Jun. PMID 28330935, Free PMC Article
  2. The Arabidopsis heat-intolerant 5 (hit5)/enhanced response to aba 1 (era1) mutant reveals the crucial role of protein farnesylation in plant responses to heat stress. Wu JR, et al. New Phytol, 2017 Feb. PMID 27673599
  3. A novel role for protein farnesylation in plant innate immunity. Goritschnig S, et al. Plant Physiol, 2008 Sep. PMID 18599656, Free PMC Article
  4. Functional requirement of plant farnesyltransferase during development in Arabidopsis. Yalovsky S, et al. Plant Cell, 2000 Aug. PMID 10948248, Free PMC Article
  5. Cloning of the Arabidopsis WIGGUM gene identifies a role for farnesylation in meristem development. Ziegelhoffer EC, et al. Proc Natl Acad Sci U S A, 2000 Jun 20. PMID 10840062, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A role for ERA1 in blue light-induced stomatal opening, pathogen immunity and disease resistance
    Title: The Role of ENHANCED RESPONSES TO ABA1 (ERA1) in Arabidopsis Stomatal Responses Is Beyond ABA Signaling.
  2. Map-based cloning revealed that HIT5 encodes the beta-subunit of the protein farnesyltransferase.
    Title: The Arabidopsis heat-intolerant 5 (hit5)/enhanced response to aba 1 (era1) mutant reveals the crucial role of protein farnesylation in plant responses to heat stress.
  3. farnesyltransferase in plant-pathogen interactions, mutants display enhanced susceptibility to virulent bacterial and oomycete pathogens
    Title: A novel role for protein farnesylation in plant innate immunity.
  4. Used to demonstrate the feasibility of bimolecular fluorescence complementation in plants.
    Title: Detection of protein-protein interactions in plants using bimolecular fluorescence complementation.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001344319.1
NM_123392.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables farnesyltranstransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein farnesyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein farnesyltransferase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables protein farnesyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables zinc ion binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cutin-based cuticle development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within negative regulation of abscisic acid-activated signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of abscisic acid-activated signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein farnesylation ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within protein prenylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of meristem structural organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of response to osmotic stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of response to salt stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to abscisic acid IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to fungus IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within response to water deprivation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within stomatal opening IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of protein farnesyltransferase complex IMP
Inferred from Mutant Phenotype
more info
 PubMed 
part_of protein farnesyltransferase complex ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
Prenyltransferase family protein
NP_198844.1
  • ENHANCED RESPONSE TO ABA 1 (ERA1); CONTAINS InterPro DOMAIN/s: Terpenoid cylases/protein prenyltransferase alpha-alpha toroid (InterPro:IPR008930), Prenyltransferase/squalene oxidase (InterPro:IPR001330); BEST Arabidopsis thaliana protein match is: RAB geranylgeranyl transferase beta subunit 2 (TAIR:AT3G12070.2); Has 2257 Blast hits to 1610 proteins in 263 species: Archae - 4; Bacteria - 30; Metazoa - 707; Fungi - 630; Plants - 303; Viruses - 4; Other Eukaryotes - 579 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    16101343..16104962
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_123392.2 → NP_198844.1  Prenyltransferase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_198844.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4VCL6, Q38916, Q38920, Q8LPK8, Q9LLE9
    UniProtKB/TrEMBL
    A0A5S9Y9M8, A0A654G6R0
    Conserved Domains (1) summary
    PLN02710
    Location:42 → 482
    PLN02710; farnesyltranstransferase subunit beta

  2. NM_001344319.1 → NP_001331518.1  Prenyltransferase family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BE65, A0A5S9Y9M8
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q38920.3

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