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PFD5 prefoldin 5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 832393, updated on 7-Sep-2023

Summary

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Gene symbol
PFD5
Gene description
prefoldin 5
Primary source
Araport:AT5G23290
Locus tag
AT5G23290
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
MKD15.15; MKD15_15; prefoldin 5
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Genomic context

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See PFD5 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
4
Sequence:
Chromosome: 5; NC_003076.8 (7846081..7847643)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene sugar transporter 11 Neighboring gene TCP family transcription factor Neighboring gene pyrimidine d Neighboring gene Fe superoxide dismutase 3 Neighboring gene S-isoprenylcysteine O-methyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dynamic regulation of cortical microtubule organization through prefoldin-DELLA interaction. Locascio A, et al. Curr Biol, 2013 May 6. PMID 23583555
  2. Prefoldin 6 is required for normal microtubule dynamics and organization in Arabidopsis. Gu Y, et al. Proc Natl Acad Sci U S A, 2008 Nov 18. PMID 19004800, Free PMC Article
  3. Prefoldins 3 and 5 play an essential role in Arabidopsis tolerance to salt stress. Rodríguez-Milla MA, et al. Mol Plant, 2009 May. PMID 19825635
  4. Prefoldins contribute to maintaining the levels of the spliceosome LSM2-8 complex through Hsp90 in Arabidopsis. Esteve-Bruna D, et al. Nucleic Acids Res, 2020 Jun 19. PMID 32396196, Free PMC Article
  5. Prefoldins Negatively Regulate Cold Acclimation in Arabidopsis thaliana by Promoting Nuclear Proteasome-Mediated HY5 Degradation. Perea-Resa C, et al. Mol Plant, 2017 Jun 5. PMID 28412546

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_122235.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables unfolded protein binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cellular response to gibberellin stimulus IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_negative_effect cold acclimation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cortical microtubule organization IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_positive_effect mRNA processing ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in protein folding IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to cold IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to salt stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plastid HDA PubMed 
part_of prefoldin complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
prefoldin 5
NP_197720.1
  • prefoldin 5 (PFD5); FUNCTIONS IN: unfolded protein binding; INVOLVED IN: protein folding; LOCATED IN: prefoldin complex; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Prefoldin alpha-like (InterPro:IPR004127), Prefoldin (InterPro:IPR009053), Prefoldin alpha subunit (InterPro:IPR011599); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    7846081..7847643
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_122235.2 → NP_197720.1  prefoldin 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_197720.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P57742
    UniProtKB/TrEMBL
    A0A178UJZ9, A0A5S9Y8U5
    Conserved Domains (1) summary
    TIGR00293
    Location:15 → 141
    TIGR00293; prefoldin, archaeal alpha subunit/eukaryotic subunit 5
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P57742.1

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