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SDG4 SET domain group 4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 829210, updated on 7-Sep-2023

Summary

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Gene symbol
SDG4
Gene description
SET domain group 4
Primary source
Araport:AT4G30860
Locus tag
AT4G30860
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ASH1-related 3; ASH1-RELATED 3; ASHR3; F6I18.230; F6I18_230; SET domain group 4
Summary
Encodes a member of the trxG protein family. Contains a SET domain which is known to be involved in modification of histone tails by methylation. Interacts physically with AMS, but the implications of this interaction are unknown.Overexpression results in plieotrophic developmental defects.
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Genomic context

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Location:
chromosome: 4
Exon count:
11
Sequence:
Chromosome: 4; NC_003075.7 (15024444..15027672)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene DNA-directed RNA polymerase subunit beta Neighboring gene heptahelical transmembrane protein2 Neighboring gene Restriction endonuclease, type II-like superfamily protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Arabidopsis SDG4 contributes to the regulation of pollen tube growth by methylation of histone H3 lysines 4 and 36 in mature pollen. Cartagena JA, et al. Dev Biol, 2008 Mar 15. PMID 18252252
  2. The Arabidopsis SET-domain protein ASHR3 is involved in stamen development and interacts with the bHLH transcription factor ABORTED MICROSPORES (AMS). Thorstensen T, et al. Plant Mol Biol, 2008 Jan. PMID 17978851
  3. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
  4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
  5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_119233.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
NOT enables histone methyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
part_of chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
SET domain group 4
NP_567859.1
  • SET domain group 4 (SDG4); CONTAINS InterPro DOMAIN/s: SET domain (InterPro:IPR001214), Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Zinc finger, PHD-type (InterPro:IPR001965), Post-SET domain (InterPro:IPR003616), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), AWS (InterPro:IPR006560); BEST Arabidopsis thaliana protein match is: histone-lysine N-methyltransferase ASHH3 (TAIR:AT2G44150.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    15024444..15027672
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_119233.2 → NP_567859.1  SET domain group 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_567859.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O65563, Q949T8
    UniProtKB/TrEMBL
    A0A178UX33, A0A654FUG2
    Conserved Domains (3) summary
    smart00570
    Location:286 → 326
    AWS; associated with SET domains
    cd15565
    Location:121 → 167
    PHD2_NSD; PHD finger 2 found in nuclear receptor-binding SET domain-containing (NSD) proteins
    cd19175
    Location:327 → 465
    SET_ASHR3-like; SET domain (including post-SET domain) found in Arabidopsis thaliana ASH1-related protein 3 (ASHR3) and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q949T8.1

Gene LinkOut

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