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AT4G19510 Disease resistance protein (TIR-NBS-LRR class) [ Arabidopsis thaliana (thale cress) ]

Gene ID: 827692, updated on 15-Feb-2024

Summary

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Gene symbol
AT4G19510
Gene description
Disease resistance protein (TIR-NBS-LRR class)
Primary source
Araport:AT4G19510
Locus tag
AT4G19510
See related
TAIR:AT4G19510
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F24J7.70; F24J7_70
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Genomic context

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See AT4G19510 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
6
Sequence:
Chromosome: 4; NC_003075.7 (10633619..10639036)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene VPS54 Neighboring gene nucleoside-triphosphatase/transmembrane receptor/nucleotide binding/ATP binding protein Neighboring gene disease resistance protein (TIR-NBS-LRR class) family Neighboring gene disease resistance protein (TIR-NBS-LRR class) family

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
  2. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198
  3. Multi-omics network-based functional annotation of unknown Arabidopsis genes. Depuydt T, et al. Plant J, 2021 Nov. PMID 34562334

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001341344.1
NM_001341351.1
NM_118071.6
NM_179079.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ADP binding IEA
Inferred from Electronic Annotation
more info
  
enables NAD+ nucleotidase, cyclic ADP-ribose generating IEA
Inferred from Electronic Annotation
more info
  
enables NADP+ nucleosidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Disease resistance protein (TIR-NBS-LRR class)
NP_193686.5
  • Disease resistance protein (TIR-NBS-LRR class); FUNCTIONS IN: transmembrane receptor activity, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Disease resistance protein (InterPro:IPR000767), Toll-Interleukin receptor (InterPro:IPR000157); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT4G12010.1); Has 24495 Blast hits to 16844 proteins in 780 species: Archae - 22; Bacteria - 1657; Metazoa - 3405; Fungi - 143; Plants - 18330; Viruses - 4; Other Eukaryotes - 934 (source: NCBI BLink).
NP_849410.1
  • Disease resistance protein (TIR-NBS-LRR class); FUNCTIONS IN: transmembrane receptor activity, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane, endomembrane system; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Disease resistance protein (InterPro:IPR000767), Toll-Interleukin receptor (InterPro:IPR000157); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT4G12010.1); Has 17554 Blast hits to 12982 proteins in 513 species: Archae - 8; Bacteria - 748; Metazoa - 631; Fungi - 25; Plants - 15570; Viruses - 0; Other Eukaryotes - 572 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    10633619..10639036
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001341345.1 → NP_001328451.1  Disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B4P3

  2. NM_001341346.1 → NP_001328448.1  Disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A1P8B4Q1, F4JT80, O49469

  3. NM_001341347.1 → NP_001328447.1  Disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A1P8B4Q1, F4JT80, O49469

  4. NM_001341348.1 → NP_001328450.1  Disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A1P8B4Q1, F4JT80, O49469
    UniProtKB/TrEMBL
    A0A1P8B4P2

  5. NM_001341349.1 → NP_001328449.1  Disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A1P8B4Q1, F4JT80, O49469

  6. NM_001341350.1 → NP_001328446.1  Disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A1P8B4Q1, F4JT80, O49469

  7. NM_118071.6 → NP_193686.5  Disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_193686.5

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A1P8B4Q1, F4JT80, O49469
    Conserved Domains (4) summary
    PLN03210
    Location:57 → 1139
    PLN03210; Resistant to P. syringae 6; Provisional
    sd00033
    Location:682 → 704
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:633 → 658
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam01582
    Location:57 → 221
    TIR; TIR domain

  8. NM_001341351.1 → NP_001328445.1  Disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B4P0

  9. NM_179079.2 → NP_849410.1  Disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849410.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A1P8B4Q1, F4JT80, O49469
    UniProtKB/TrEMBL
    F4JT81
    Conserved Domains (5) summary
    COG4886
    Location:594 → 820
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:610 → 627
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:702 → 745
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam00931
    Location:198 → 442
    NB-ARC; NB-ARC domain
    pfam01582
    Location:17 → 181
    TIR; TIR domain

  10. NM_001341344.1 → NP_001328444.1  Disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B4P4
Nucleotide Protein
Heading Accession and Version

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