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THO7 Tho complex subunit 7/Mft1p [ Arabidopsis thaliana (thale cress) ]

Gene ID: 821174, updated on 15-Oct-2023

Summary

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Gene symbol
THO7
Gene description
Tho complex subunit 7/Mft1p
Primary source
Araport:AT3G02950
Locus tag
AT3G02950
See related
TAIR:AT3G02950
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtTHO7; F13E7.10; F13E7_10
Summary
Encodes a component of the putative Arabidopsis THO/TREX complex: THO1 or HPR1 (At5g09860), THO2 (At1g24706), THO3 or TEX1 (At5g56130), THO5 (At5g42920, At1g45233), THO6 (At2g19430), and THO7 (At5g16790, At3g02950). THO/TREX complexes in animals have been implicated in the transport of mRNA precursors. Mutants of THO3/TEX1, THO1, THO6 accumulate reduced amount of small interfering (si)RNA, suggesting a role of the putative Arabidopsis THO/TREX in siRNA biosynthesis.
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Genomic context

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See THO7 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
3
Sequence:
Chromosome: 3; NC_003074.8 (665223..666922, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene weak chloroplast movement under blue light protein (DUF827) Neighboring gene myb domain protein 107 Neighboring gene Heavy metal transport/detoxification superfamily protein Neighboring gene uncharacterized protein Neighboring gene EXORDIUM like 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Putative Arabidopsis THO/TREX mRNA export complex is involved in transgene and endogenous siRNA biosynthesis. Yelina NE, et al. Proc Natl Acad Sci U S A, 2010 Aug 3. PMID 20634427, Free PMC Article
  2. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
  3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001337451.1
NM_111165.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
part_of THO complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of THO complex part of transcription export complex IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Tho complex subunit 7/Mft1p
NP_566189.1
  • THO7; CONTAINS InterPro DOMAIN/s: Tho complex subunit 7 (InterPro:IPR018018), Tho complex subunit 7/Mft1p (InterPro:IPR008501); BEST Arabidopsis thaliana protein match is: Tho complex subunit 7/Mft1p (TAIR:AT5G16790.1); Has 2509 Blast hits to 2230 proteins in 391 species: Archae - 54; Bacteria - 255; Metazoa - 1226; Fungi - 237; Plants - 121; Viruses - 25; Other Eukaryotes - 591 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    665223..666922 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_111165.4 → NP_566189.1  Tho complex subunit 7/Mft1p [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_566189.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9M8T6
    UniProtKB/TrEMBL
    A0A178VDN6, A0A5S9X8L5
    Conserved Domains (1) summary
    pfam05615
    Location:29 → 166
    THOC7; Tho complex subunit 7

  2. NM_001337451.1 → NP_001327695.1  Tho complex subunit 7/Mft1p [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9M8T6
    UniProtKB/TrEMBL
    A0A178VDN6, A0A5S9X8L5
    Conserved Domains (1) summary
    pfam05615
    Location:29 → 166
    THOC7; Tho complex subunit 7
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9M8T6.1

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