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LOG2 RING/U-box superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 820135, updated on 18-Sep-2024

Summary

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Official Symbol
LOG2
Official Full Name
RING/U-box superfamily protein
Primary source
TAIR:AT3G09770
Locus tag
AT3G09770
See related
Araport:AT3G09770
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ABA insensitive RING protein 3; AIRP3; AtAIRP3; F11F8.36; LOSS OF GDU 2
Summary
Encodes a ubiquitin E3 ligase LOG2 (LOSS OF GDU2). Required for GLUTAMINE DUMPER1(GDU1)-induced amino secretion.
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Genomic context

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Location:
chromosome: 3
Exon count:
3
Sequence:
Chromosome: 3; NC_003074.8 (2996179..2998255, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene syntaxin of plants 71 Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene RING/U-box superfamily protein Neighboring gene CRINKLY4 related 1 Neighboring gene ubiquitin 8

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Control of Amino Acid Homeostasis by a Ubiquitin Ligase-Coactivator Protein Complex. Guerra D, et al. J Biol Chem, 2017 Mar 3. PMID 28100770, Free PMC Article
  2. The Arabidopsis RING E3 ubiquitin ligase AtAIRP3/LOG2 participates in positive regulation of high-salt and drought stress responses. Kim JH, et al. Plant Physiol, 2013 Jul. PMID 23696092, Free PMC Article
  3. Functional conservation between mammalian MGRN1 and plant LOG2 ubiquitin ligases. Guerra DD, et al. FEBS Lett, 2013 Nov 1. PMID 24036454, Free PMC Article
  4. The ubiquitin E3 ligase LOSS OF GDU2 is required for GLUTAMINE DUMPER1-induced amino acid secretion in Arabidopsis. Pratelli R, et al. Plant Physiol, 2012 Apr. PMID 22291198, Free PMC Article
  5. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. GDU1 activates LOG2 to stimulate amino acid export, a process that could be negatively regulated by GDU1 ubiquitination and LOG2 self-ubiquitination.
    Title: Control of Amino Acid Homeostasis by a Ubiquitin Ligase-Coactivator Protein Complex.
  2. LOG2 plays dual functions in drought stress response and amino acid transport in Arabidopsis.LOG2 participates in positive regulation of high-salt stress response.
    Title: The Arabidopsis RING E3 ubiquitin ligase AtAIRP3/LOG2 participates in positive regulation of high-salt and drought stress responses.
  3. Interaction of GDU1 and the ubiquitin ligase LOG2 plays a significant role in the regulation of amino acid export from plant cells.[LOG2]
    Title: The ubiquitin E3 ligase LOSS OF GDU2 is required for GLUTAMINE DUMPER1-induced amino acid secretion in Arabidopsis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_111812.4
NM_180216.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin-protein transferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within abscisic acid-activated signaling pathway involved in stomatal movement IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in abscisic acid-activated signaling pathway involved in stomatal movement IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within intracellular amino acid homeostasis IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in intracellular amino acid homeostasis IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of stomatal closure IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of stomatal closure IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to abscisic acid IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to abscisic acid IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
RING/U-box superfamily protein
NP_566356.1
  • RING/U-box superfamily protein; FUNCTIONS IN: zinc ion binding; INVOLVED IN: N-terminal protein myristoylation; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841); BEST Arabidopsis thaliana protein match is: RING/U-box superfamily protein (TAIR:AT5G03200.1); Has 9681 Blast hits to 6810 proteins in 512 species: Archae - 8; Bacteria - 442; Metazoa - 3215; Fungi - 970; Plants - 3369; Viruses - 475; Other Eukaryotes - 1202 (source: NCBI BLink).
NP_850547.1
  • RING/U-box superfamily protein; FUNCTIONS IN: zinc ion binding; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; BEST Arabidopsis thaliana protein match is: RING/U-box superfamily protein (TAIR:AT5G03200.1); Has 7619 Blast hits to 4715 proteins in 450 species: Archae - 8; Bacteria - 442; Metazoa - 2165; Fungi - 884; Plants - 2938; Viruses - 368; Other Eukaryotes - 814 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    2996179..2998255 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_111812.4 → NP_566356.1  RING/U-box superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_566356.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9S752
    UniProtKB/TrEMBL
    A0A178VJI4, A0A5S9XAI9
    Conserved Domains (1) summary
    cd16789
    Location:318 → 358
    mRING-HC-C3HC5_MGRN1_like---blasttree; Modified RING finger, HC subclass (C3HC5-type), found in mahogunin RING finger protein 1 (MGRN1), RING finger protein 157 (RNF157) and similar proteins

  2. NM_180216.1 → NP_850547.1  RING/U-box superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_850547.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4J1B3
    Conserved Domains (1) summary
    pfam13920
    Location:317 → 338
    zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9S752.1

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