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PAS_chr2-2_0145 Isozyme of methylenetetrahydrofolate reductase [ Komagataella phaffii GS115 ]

Gene ID: 8198723, updated on 23-Nov-2023

Summary

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Gene symbol
PAS_chr2-2_0145
Gene description
Isozyme of methylenetetrahydrofolate reductase
Locus tag
PAS_chr2-2_0145
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Komagataella phaffii GS115 (strain: GS115)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Phaffomycetaceae; Komagataella
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Genomic context

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See PAS_chr2-2_0145 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
2
Sequence:
Chromosome: 2; NC_012964.1 (2111973..2113822, complement)

Chromosome 2 - NC_012964.1Genomic Context describing neighboring genes Neighboring gene Cell wall protein that contains a putative GPI-attachment site Neighboring gene Hypothetical protein Neighboring gene Protein involved in bud-site selection Neighboring gene Component of the Trk1p-Trk2p potassium transport system

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_012964.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the recombinant protein production host Pichia pastoris. De Schutter K, et al. Nat Biotechnol, 2009 Jun. PMID 19465926

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables FAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methylenetetrahydrofolate reductase (NAD(P)H) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in methionine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
Isozyme of methylenetetrahydrofolate reductase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_012964.1 Reference assembly

    Range
    2111973..2113822 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002492015.1 → XP_002492060.1  Isozyme of methylenetetrahydrofolate reductase [Komagataella phaffii GS115]

    See identical proteins and their annotated locations for XP_002492060.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    C4R2Q6, F2QR20
    Conserved Domains (1) summary
    cl00246
    Location:20 → 587
    MTHFR; Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase ...
Nucleotide Protein
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