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GRF9 general regulatory factor 9 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 818859, updated on 7-Sep-2023

Summary

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Gene symbol
GRF9
Gene description
general regulatory factor 9
Primary source
Araport:AT2G42590
Locus tag
AT2G42590
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F14N22.14; F14N22_14; general regulatory factor 9; GF14 MU
Summary
14-3-3 gene. Binds calcium and displays induced structural changes.
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Genomic context

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Location:
chromosome: 2
Exon count:
7
Sequence:
Chromosome: 2; NC_003071.7 (17731830..17733982, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene late embryogenesis abundant domain-containing protein / LEA domain-containing protein Neighboring gene TRICHOME BIREFRINGENCE-LIKE 39 Neighboring gene tetratricopetide-repeat thioredoxin-like 3 Neighboring gene phosphoenolpyruvate carboxylase 2 Neighboring gene LIGHT-DEPENDENT SHORT HYPOCOTYLS-like protein (DUF640)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Involvement of 14-3-3 protein GRF9 in root growth and response under polyethylene glycol-induced water stress. He Y, et al. J Exp Bot, 2015 Apr. PMID 25873671, Free PMC Article
  2. The 14-3-3 proteins of Arabidopsis regulate root growth and chloroplast development as components of the photosensory system. Mayfield JD, et al. J Exp Bot, 2012 May. PMID 22378945, Free PMC Article
  3. Exposed loop domains of complexed 14-3-3 proteins contribute to structural diversity and functional specificity. Sehnke PC, et al. Plant Physiol, 2006 Feb. PMID 16407442, Free PMC Article
  4. GROWTH-REGULATING FACTOR 9 negatively regulates arabidopsis leaf growth by controlling ORG3 and restricting cell proliferation in leaf primordia. Omidbakhshfard MA, et al. PLoS Genet, 2018 Jul. PMID 29985961, Free PMC Article
  5. The Arabidopsis F-box protein AtFBS1 interacts with 14-3-3 proteins. Sepúlveda-García E, et al. Plant Sci, 2012 Oct. PMID 22920997

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Study identified ORG3 as a direct downstream, and positively regulated target of GRF9. Genetic analysis of grf9 org3 and GRF9ox org3 double mutants reveals that both transcription factors act in a regulatory cascade to control the final leaf dimensions by restricting cell number in the developing leaf in Arabidopsis thaliana.
    Title: GROWTH-REGULATING FACTOR 9 negatively regulates arabidopsis leaf growth by controlling ORG3 and restricting cell proliferation in leaf primordia.
  2. GRF9 is involved in allocating more carbon from the shoot to the root and enhancing proton secretion in the root growing zone, and this process is important for root response to mild water stress.
    Title: Involvement of 14-3-3 protein GRF9 in root growth and response under polyethylene glycol-induced water stress.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001036455.1
NM_001036456.1
NM_129820.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables calcium ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein phosphorylated amino acid binding TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within post-embryonic root development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast stroma IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chloroplast stroma IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in cytoplasm HDA PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in cytosol HDA PubMed 
located_in nucleus HDA PubMed 
located_in plasma membrane HDA PubMed 

General protein information

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Preferred Names
general regulatory factor 9
NP_001031532.1
  • general regulatory factor 9 (GRF9); FUNCTIONS IN: protein phosphorylated amino acid binding, calcium ion binding; LOCATED IN: chloroplast stroma, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: 14-3-3 protein (InterPro:IPR000308); BEST Arabidopsis thaliana protein match is: general regulatory factor 12 (TAIR:AT1G26480.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_001031533.1
  • general regulatory factor 9 (GRF9); FUNCTIONS IN: protein phosphorylated amino acid binding, calcium ion binding; LOCATED IN: chloroplast stroma, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: 14-3-3 protein (InterPro:IPR000308); BEST Arabidopsis thaliana protein match is: general regulatory factor 12 (TAIR:AT1G26480.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_565977.1
  • general regulatory factor 9 (GRF9); FUNCTIONS IN: protein phosphorylated amino acid binding, calcium ion binding; LOCATED IN: chloroplast stroma, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: 14-3-3 protein (InterPro:IPR000308); BEST Arabidopsis thaliana protein match is: general regulatory factor 12 (TAIR:AT1G26480.1); Has 2711 Blast hits to 2702 proteins in 385 species: Archae - 0; Bacteria - 4; Metazoa - 1258; Fungi - 332; Plants - 762; Viruses - 0; Other Eukaryotes - 355 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    17731830..17733982 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_129820.3 → NP_565977.1  general regulatory factor 9 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_565977.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O80367, Q96299
    UniProtKB/TrEMBL
    A0A178VYW7, A0A5S9X6G7
    Conserved Domains (1) summary
    pfam00244
    Location:13 → 234
    14-3-3; 14-3-3 protein

  2. NM_001036455.1 → NP_001031532.1  general regulatory factor 9 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031532.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4IP53
    Conserved Domains (1) summary
    pfam00244
    Location:11 → 237
    14-3-3; 14-3-3 protein

  3. NM_001036456.1 → NP_001031533.1  general regulatory factor 9 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031533.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4IP55
    Conserved Domains (1) summary
    pfam00244
    Location:11 → 237
    14-3-3; 14-3-3 protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q96299.2

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