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TIM44-2 translocase inner membrane subunit 44-2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 818180, updated on 7-Sep-2023

Summary

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Gene symbol
TIM44-2
Gene description
translocase inner membrane subunit 44-2
Primary source
Araport:AT2G36070
Locus tag
AT2G36070
See related
TAIR:AT2G36070
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATTIM44-2; F11F19.2; F11F19_2; translocase inner membrane subunit 44-2
Summary
One of two genes in Arabidopsis that encode a putative subunit of the mitochondrial inner membrane translocase complex. TIM44 subunit is thought to provide the energy for translocation via hydrolysis of ATP.
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Genomic context

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See TIM44-2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
14
Sequence:
Chromosome: 2; NC_003071.7 (15144795..15148223, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ovate family protein 15 Neighboring gene MMS ZWEI homologue 3 Neighboring gene AP2/B3-like transcriptional factor family protein Neighboring gene F-box family protein Neighboring gene Uncharacterized protein family (UPF0497)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification, expression, and import of components 17 and 23 of the inner mitochondrial membrane translocase from Arabidopsis. Murcha MW, et al. Plant Physiol, 2003 Apr. PMID 12692332, Free PMC Article
  2. A transcriptomic and proteomic characterization of the Arabidopsis mitochondrial protein import apparatus and its response to mitochondrial dysfunction. Lister R, et al. Plant Physiol, 2004 Feb. PMID 14730085, Free PMC Article
  3. Heterogeneity of the mitochondrial proteome for photosynthetic and non-photosynthetic Arabidopsis metabolism. Lee CP, et al. Mol Cell Proteomics, 2008 Jul. PMID 18385124
  4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

General gene information

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Homology

NM_129166.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ABC-type protein transporter activity TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within protein targeting to mitochondrion TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of TIM23 mitochondrial import inner membrane translocase complex TAS
Traceable Author Statement
more info
 PubMed 
located_in mitochondrial inner membrane HDA PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
translocase inner membrane subunit 44-2
NP_181151.3
  • translocase inner membrane subunit 44-2 (TIM44-2); FUNCTIONS IN: protein-transmembrane transporting ATPase activity; INVOLVED IN: protein targeting to mitochondrion; LOCATED IN: mitochondrion, mitochondrial inner membrane, mitochondrial inner membrane presequence translocase complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Mitochondrial inner membrane translocase complex, subunit Tim44-related (InterPro:IPR007379); BEST Arabidopsis thaliana protein match is: translocase inner membrane subunit 44-1 (TAIR:AT2G20510.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    15144795..15148223 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_129166.5 → NP_181151.3  translocase inner membrane subunit 44-2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_181151.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q5XF06, Q8S8E5
    UniProtKB/TrEMBL
    A0A178VXX7, A0A7G2EHS2
    Conserved Domains (2) summary
    TIGR00984
    Location:55 → 459
    3a0801s03tim44; mitochondrial import inner membrane, translocase subunit
    pfam04280
    Location:311 → 460
    Tim44; Tim44-like domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XF06.1

Gene LinkOut

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