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DSK2 ubiquitin family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 816225, updated on 7-Sep-2023

Summary

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Gene symbol
DSK2
Gene description
ubiquitin family protein
Primary source
Araport:AT2G17200
Locus tag
AT2G17200
See related
TAIR:AT2G17200
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
DSK2b; T23A1.6; T23A1_6
Summary
Encodes a ubiquitin receptor protein that specifically associates with PEX2 and PEX12.
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Genomic context

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See DSK2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
8
Sequence:
Chromosome: 2; NC_003071.7 (7481881..7485240, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene C2H2-like zinc finger protein Neighboring gene ubiquitin family protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene Protein kinase superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Selective Autophagy of BES1 Mediated by DSK2 Balances Plant Growth and Survival. Nolan TM, et al. Dev Cell, 2017 Apr 10. PMID 28399398, Free PMC Article
  2. Arabidopsis RING peroxins are E3 ubiquitin ligases that interact with two homologous ubiquitin receptor proteins(F). Kaur N, et al. J Integr Plant Biol, 2013 Jan. PMID 23336935
  3. The defective proteasome but not substrate recognition function is responsible for the null phenotypes of the Arabidopsis proteasome subunit RPN10. Lin YL, et al. Plant Cell, 2011 Jul. PMID 21764993, Free PMC Article
  4. Autophagic Degradation of the 26S Proteasome Is Mediated by the Dual ATG8/Ubiquitin Receptor RPN10 in Arabidopsis. Marshall RS, et al. Mol Cell, 2015 Jun 18. PMID 26004230, Free PMC Article
  5. Cross-species divergence of the major recognition pathways of ubiquitylated substrates for ubiquitin/26S proteasome-mediated proteolysis. Fatimababy AS, et al. FEBS J, 2010 Feb. PMID 20059542

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. BES1 interacts with the ubiquitin receptor protein DSK2 and is targeted to the autophagy pathway during stress.
    Title: Selective Autophagy of BES1 Mediated by DSK2 Balances Plant Growth and Survival.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_127274.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables polyubiquitin modification-dependent protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
ubiquitin family protein
NP_179311.1
  • DSK2; CONTAINS InterPro DOMAIN/s: Heat shock chaperonin-binding (InterPro:IPR006636), Ubiquitin-associated/translation elongation factor EF1B, N-terminal (InterPro:IPR000449), Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote (InterPro:IPR015940), Ubiquilin (InterPro:IPR015496), Ubiquitin (InterPro:IPR000626), Ubiquitin supergroup (InterPro:IPR019955), UBA-like (InterPro:IPR009060); BEST Arabidopsis thaliana protein match is: ubiquitin family protein (TAIR:AT2G17190.1); Has 15379 Blast hits to 7776 proteins in 854 species: Archae - 6; Bacteria - 3440; Metazoa - 5160; Fungi - 1735; Plants - 2506; Viruses - 174; Other Eukaryotes - 2358 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    7481881..7485240 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_127274.3 → NP_179311.1  ubiquitin family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_179311.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q94C51, Q9SII8
    UniProtKB/TrEMBL
    A0A5S9WYY8, A0A654EYL8
    Conserved Domains (4) summary
    smart00727
    Location:383 → 418
    STI1; Heat shock chaperonin-binding motif
    cd14399
    Location:508 → 547
    UBA_PLICs; UBA domain of eukaryotic protein linking integrin-associated protein (IAP, also known as CD47) with cytoskeleton (PLIC) proteins
    TIGR00601
    Location:402 → 546
    rad23; UV excision repair protein Rad23
    cd16106
    Location:18 → 89
    Ubl_Dsk2p_like; ubiquitin-like (Ubl) domain found in Saccharomyces cerevisiae proteasome interacting protein Dsk2p and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SII8.1

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