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PF3D7_0918600 ATP-dependent DNA helicase Q1 [ Plasmodium falciparum 3D7 ]

Gene ID: 813462, updated on 17-May-2024

Summary

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Gene symbol
PF3D7_0918600
Gene description
ATP-dependent DNA helicase Q1
Primary source
PlasmoDB:PF3D7_0918600
Locus tag
PF3D7_0918600
See related
VEuPathDB:PF3D7_0918600
Gene type
protein coding
RNA name
ATP-dependent DNA helicase Q1
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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See PF3D7_0918600 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
1
Sequence:
Chromosome: 9; NC_004330.2 (764848..767034)

Chromosome 9 - NC_004330.2Genomic Context describing neighboring genes Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene ncRNA Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene dihydrouridine synthase, putative

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_004330.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. DNA helicase RecQ1 regulates mutually exclusive expression of virulence genes in Plasmodium falciparum via heterochromatin alteration. Li Z, et al. Proc Natl Acad Sci U S A, 2019 Feb 19. PMID 30728298, Free PMC Article
  2. Plasmodium falciparum Bloom homologue, a nucleocytoplasmic protein, translocates in 3' to 5' direction and is essential for parasite growth. Rahman F, et al. Biochim Biophys Acta, 2016 May. PMID 26917473
  3. Characterization of recombinant malarial RecQ DNA helicase. Suntornthiticharoen P, et al. Mol Biochem Parasitol, 2014 Aug. PMID 25111966
  4. RecQ helicases in the malaria parasite Plasmodium falciparum affect genome stability, gene expression patterns and DNA replication dynamics. Claessens A, et al. PLoS Genet, 2018 Jul. PMID 29965959, Free PMC Article
  5. Elucidation of an essential function of the unique charged domain of Plasmodium topoisomerase III. Bansod S, et al. Biochem J, 2020 Nov 26. PMID 33241842

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables 3'-5' DNA helicase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ATP hydrolysis activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA duplex unwinding IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within DNA repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within epigenetic regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within mitochondrial double-strand break repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within telomere maintenance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
ATP-dependent DNA helicase Q1
XP_001352057.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004330.2 Reference assembly

    Range
    764848..767034
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001352021.1 → XP_001352057.1  ATP-dependent DNA helicase Q1 [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001352057.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A024V6D1, A0A024W9E2, A0A024WSR7, A0A0L1I564, A0A0L7K8W3, Q8I2W7, W4IHH1, W7FN02, W7FW12, W7JXN8
    Conserved Domains (1) summary
    COG0514
    Location:41 → 482
    RecQ; Superfamily II DNA helicase RecQ [Replication, recombination and repair]
Nucleotide Protein
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