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PF3D7_1008000 histone deacetylase 2 [ Plasmodium falciparum 3D7 ]

Gene ID: 810236, updated on 17-May-2024

Summary

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Gene symbol
PF3D7_1008000
Gene description
histone deacetylase 2
Primary source
PlasmoDB:PF3D7_1008000
Locus tag
PF3D7_1008000
Gene type
protein coding
RNA name
histone deacetylase 2
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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See PF3D7_1008000 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
1
Sequence:
Chromosome: 10; NC_037281.1 (321011..328150)

Chromosome 10 - NC_037281.1Genomic Context describing neighboring genes Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene eukaryotic translation initiation factor 3 subunit D, putative Neighboring gene zinc finger protein, putative Neighboring gene endonuclease, putative

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037281.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Plasmodium falciparum histone deacetylase regulates antigenic variation and gametocyte conversion. Coleman BI, et al. Cell Host Microbe, 2014 Aug 13. PMID 25121747, Free PMC Article
  2. A Plasmodium multi-domain protein possesses multiple inositol phosphate kinase activities. Stritzke C, et al. Mol Biochem Parasitol, 2012 Dec. PMID 23123170
  3. Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum. Oehring SC, et al. Genome Biol, 2012 Nov 26. PMID 23181666, Free PMC Article
  4. A protein interaction network of the malaria parasite Plasmodium falciparum. LaCount DJ, et al. Nature, 2005 Nov 3. PMID 16267556
  5. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PfHda2 depletion leads to dysregulated expression of both virulence-associated var genes.
    Title: A Plasmodium falciparum histone deacetylase regulates antigenic variation and gametocyte conversion.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by GeneDB

Process Evidence Code Pubs
acts_upstream_of_or_within inositol phosphate biosynthetic process ISO
Inferred from Sequence Orthology
more info
 PubMed 
acts_upstream_of_or_within regulation of gene expression IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus HDA PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
histone deacetylase 2
XP_001347363.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_037281.1 Reference assembly

    Range
    321011..328150
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001347327.1 → XP_001347363.1  histone deacetylase 2 [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001347363.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0L1I9I7, A0A2I0BQY8, Q8IJW3
    Conserved Domains (3) summary
    cd09992
    Location:961 → 1287
    HDAC_classII; Histone deacetylases and histone-like deacetylases, classII
    cl12283
    Location:2090 → 2236
    IPK; Inositol polyphosphate kinase
    cl17011
    Location:515 → 625
    Arginase_HDAC; Arginase-like and histone-like hydrolases
Nucleotide Protein
Heading Accession and Version

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