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LOC8026394 presenilin-1-like [ Ixodes scapularis (black-legged tick) ]

Gene ID: 8026394, updated on 26-Mar-2024

Summary

Gene symbol
LOC8026394
Gene description
presenilin-1-like
See related
VectorBase:ISCP_037720; EnsemblRapid:LOC8026394
Gene type
protein coding
RefSeq status
MODEL
Organism
Ixodes scapularis
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes
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Genomic context

Location:
chromosome: Un
Exon count:
1
Annotation release Status Assembly Chr Location
103 current ASM1692078v2 (GCF_016920785.2) Unplaced Scaffold NW_024609868.1 (90579130..90580359)
102 previous assembly Ixodes_scapularus_ComboLowHiFi (GCF_016920785.1) Unplaced Scaffold NW_024388633.1 (1448321..1449550, complement)

NW_024609868.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120847476 Neighboring gene uncharacterized LOC115314536 Neighboring gene solute carrier family 22 member 7-like Neighboring gene uncharacterized LOC121837226

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic endopeptidase activity, intramembrane cleaving IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in Notch receptor processing IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in amyloid precursor protein catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in amyloid-beta metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in calcium ion transport IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein processing IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cell surface IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in ciliary rootlet IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in dendritic shaft IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in growth cone IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in neuromuscular junction IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ixodes scapularis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1692078v2

Genomic

  1. NW_024609868.1 Reference ASM1692078v2

    Range
    90579130..90580359
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040219254.1XP_040075188.1  presenilin-1-like

    UniProtKB/TrEMBL
    B7P928
    Related
    XP_040075188.1, XM_040219254.1
    Conserved Domains (1) summary
    smart00730
    Location:75390
    PSN; Presenilin, signal peptide peptidase, family