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fyb1b FYN binding protein 1 b [ Danio rerio (zebrafish) ]

Gene ID: 796938, updated on 27-Mar-2024

Summary

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Official Symbol
fyb1bprovided by ZNC
Official Full Name
FYN binding protein 1 bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-091204-85
See related
Ensembl:ENSDARG00000044694 AllianceGenome:ZFIN:ZDB-GENE-091204-85
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fybb; si:ch211-147j13.3
Summary
Predicted to be involved in T cell receptor signaling pathway; integrin-mediated signaling pathway; and protein localization to plasma membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in thrombocytopenia. Orthologous to human FYB1 (FYN binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See fyb1b in Genome Data Viewer
Location:
chromosome: 21
Exon count:
20
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (19844156..19866353)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (19807551..19829717)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene nicotinamide nucleotide transhydrogenase Neighboring gene coiled-coil domain containing 80 like 2 Neighboring gene multifunctional ROCO family signaling regulator 1 Neighboring gene exoribonuclease 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Proteome dynamics in neutrophils of adult zebrafish upon chemically-induced inflammation. Singh SK, et al. Fish Shellfish Immunol, 2014 Sep. PMID 25014315
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
FYN-binding protein-like
Names
FYN binding protein b

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    19844156..19866353
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001923558.6 → XP_001923593.1  FYN-binding protein-like isoform X2

    UniProtKB/TrEMBL
    A0A8M1QKX1
    Related
    ENSDARP00000065673.5, ENSDART00000065674.7
    Conserved Domains (2) summary
    pfam14603
    Location:645 → 723
    hSH3; Helically-extended SH3 domain
    cl17036
    Location:411 → 479
    SH3; Src Homology 3 domain superfamily

  2. XM_009295371.3 → XP_009293646.1  FYN-binding protein-like isoform X1

    UniProtKB/TrEMBL
    A0A8M3AWV8
    Conserved Domains (2) summary
    pfam14603
    Location:658 → 736
    hSH3; Helically-extended SH3 domain
    cl17036
    Location:424 → 492
    SH3; Src Homology 3 domain superfamily

  3. XM_009295372.3 → XP_009293647.1  FYN-binding protein-like isoform X3

    UniProtKB/TrEMBL
    A0A8M3ATW5
    Conserved Domains (2) summary
    pfam14603
    Location:627 → 705
    hSH3; Helically-extended SH3 domain
    cl17036
    Location:424 → 492
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein Strain
Heading Accession and Version

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