spartb spartin b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: spartbprovided by ZNC
Official Full Name: spartin bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-060825-146
See related: Ensembl:ENSDARG00000103457 AllianceGenome:ZFIN:ZDB-GENE-060825-146
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: spg20b; zgc:153766
Summary: Predicted to be involved in cell division and negative regulation of BMP signaling pathway. Predicted to be active in plasma membrane. Is expressed in brain and skeletal muscle. Human ortholog(s) of this gene implicated in Troyer syndrome. Orthologous to human SPART (spartin). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 15

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (32798392..32801465)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (32940413..32943486)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in cell division	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of BMP signaling pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: spartin b

Names: spastic paraplegia 20b (Troyer syndrome)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001045451.1 → NP_001038916.1 spartin b

See identical proteins and their annotated locations for NP_001038916.1

Status: PROVISIONAL

Source sequence(s)

BC122416

UniProtKB/TrEMBL

Q0P3W0

Related

ENSDARP00000137120.1, ENSDART00000166525.2

Conserved Domains (1) summary

cd02679
Location:17 → 96

MIT_spastin; MIT: domain contained within Microtubule Interacting and Trafficking molecules. This MIT domain sub-family is found in the AAA protein spastin, a probable ATPase involved in the assembly or function of nuclear protein complexes; spastins might also be ...