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MCC MCC regulator of WNT signaling pathway [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 694270, updated on 17-Aug-2024

Summary

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Official Symbol
MCCprovided by VGNC
Official Full Name
MCC regulator of WNT signaling pathwayprovided by VGNC
Primary source
VGNC:VGNC:74675
See related
Ensembl:ENSMMUG00000013557
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
21
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (110536103..111010967, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (110446320..110715868, complement)

Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106998889 Neighboring gene signal recognition particle 19 Neighboring gene receptor accessory protein 5 Neighboring gene survival motor neuron protein-like Neighboring gene decapping mRNA 2 Neighboring gene 40S ribosomal protein S2 pseudogene Neighboring gene U4atac minor spliceosomal RNA Neighboring gene testis specific serine kinase 1B Neighboring gene YTH N6-methyladenosine RNA binding protein C2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
colorectal mutant cancer protein
Names
MCC, WNT signaling pathway regulator
mutated in colorectal cancers

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041759.1 Reference Mmul_10 Primary Assembly

    Range
    110536103..111010967 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028849659.1 → XP_028705492.1  colorectal mutant cancer protein isoform X1

    UniProtKB/TrEMBL
    F7FRB5, H9F9D0
    Related
    ENSMMUP00000017830.2, ENSMMUT00000019035.4
    Conserved Domains (4) summary
    COG1196
    Location:743 → 1006
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:198 → 474
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam10506
    Location:587 → 650
    MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome
    pfam13499
    Location:32 → 88
    EF-hand_7; EF-hand domain pair

  2. XM_002804475.3 → XP_002804521.1  colorectal mutant cancer protein isoform X2

    UniProtKB/TrEMBL
    A0A1D5Q4C5, F7FRA5
    Related
    ENSMMUP00000017831.1, ENSMMUT00000019036.3
    Conserved Domains (1) summary
    pfam10506
    Location:402 → 465
    MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome

  3. XM_015140595.2 → XP_014996081.1  colorectal mutant cancer protein isoform X3

    UniProtKB/TrEMBL
    A0A1D5QD96
    Conserved Domains (1) summary
    pfam10506
    Location:339 → 402
    MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome
Nucleotide Protein
Heading Accession and Version

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