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USP RXR type hormone receptor [ Bombyx mori (domestic silkworm) ]

Gene ID: 693034, updated on 3-Apr-2024

Summary

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Gene symbol
USP
Gene description
RXR type hormone receptor
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bombyx mori
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea; Bombycidae; Bombycinae; Bombyx
Also known as
Cf1; RXRB; BmCF1; BmUSP-2
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Genomic context

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Location:
chromosome: 4
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_01 current ASM3026992v2 (GCF_030269925.1) 4 NC_085110.1 (6618627..6683028)
103 previous assembly Bmori_2016v1.0 (GCF_014905235.1) 4 NC_051361.1 (6425558..6489957)

Chromosome 4 - NC_085110.1Genomic Context describing neighboring genes Neighboring gene RB1-inducible coiled-coil protein 1 Neighboring gene uncharacterized LOC110385730 Neighboring gene glucose-6-phosphate 1-dehydrogenase Zw Neighboring gene uncharacterized LOC134198750 Neighboring gene uncharacterized protein C05D11.1 Neighboring gene uncharacterized LOC134198749

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The expression profile and promoter analysis of ultraspiracle gene in the silkworm Bombyx mori. Huang MX, et al. Mol Biol Rep, 2014 Dec. PMID 25175165
  2. Silkworm 30K protein inhibits ecdysone-induced apoptosis by blocking the binding of ultraspiracle to ecdysone receptor-B1 in cultured Bm5 cells. Kim MY, et al. Arch Insect Biochem Physiol, 2012 Nov. PMID 22890884
  3. BmCF1, a Bombyx mori RXR-type receptor related to the Drosophila ultraspiracle. Tzertzinis G, et al. J Mol Biol, 1994 May 6. PMID 8176738
  4. Ecdysone receptor and ultraspiracle proteins are tyrosine phosphorylated during adult development of silkmoths. Sridhara S. Insect Biochem Mol Biol, 2012 Feb. PMID 22154755
  5. Large scale full-length cDNA sequencing reveals a unique genomic landscape in a lepidopteran model insect, Bombyx mori. Suetsugu Y, et al. G3 (Bethesda), 2013 Sep 4. PMID 23821615, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. BmUSP is expressed at different levels in different tissues of the silkworm, but all are subjected to the regulation by ecdysone.
    Title: The expression profile and promoter analysis of ultraspiracle gene in the silkworm Bombyx mori.
  2. 30K proteins bound primarily to the EcR-B1 and not to ultraspiracle.
    Title: Silkworm 30K protein inhibits ecdysone-induced apoptosis by blocking the binding of ultraspiracle to ecdysone receptor-B1 in cultured Bm5 cells.
  3. tyrosine phosphorylated coincidental with high protein tyrosine phosphorylations during growth to differentiation transition
    Title: Ecdysone receptor and ultraspiracle proteins are tyrosine phosphorylated during adult development of silkmoths.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear steroid receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein ultraspiracle homolog
Names
RXR type hormone receptor CF1
Ultraspiracle 2
nuclear receptor subfamily 2 group B member 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001044005.1 → NP_001037470.1  protein ultraspiracle homolog

    See identical proteins and their annotated locations for NP_001037470.1

    Status: PROVISIONAL

    Source sequence(s)
    U06073
    UniProtKB/Swiss-Prot
    P49700
    Conserved Domains (2) summary
    cd06956
    Location:112 → 188
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    cl11397
    Location:206 → 435
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

RefSeqs of Annotated Genomes: GCF_030269925.1-RS_2024_01

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM3026992v2 Primary Assembly

Genomic

  1. NC_085110.1 Reference ASM3026992v2 Primary Assembly

    Range
    6618627..6683028
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012692863.3 → XP_012548317.1  protein ultraspiracle homolog isoform X2

    UniProtKB/TrEMBL
    A0A8R2GAY7
    Conserved Domains (2) summary
    cd06956
    Location:58 → 134
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    cl11397
    Location:152 → 381
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

  2. XM_012692856.4 → XP_012548310.1  protein ultraspiracle homolog isoform X1

    See identical proteins and their annotated locations for XP_012548310.1

    UniProtKB/TrEMBL
    A0A8R2G9S5
    Conserved Domains (2) summary
    cd06956
    Location:112 → 188
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    cl11397
    Location:206 → 435
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

  3. XM_012692855.4 → XP_012548309.1  protein ultraspiracle homolog isoform X1

    See identical proteins and their annotated locations for XP_012548309.1

    UniProtKB/TrEMBL
    A0A8R2G9S5
    Conserved Domains (2) summary
    cd06956
    Location:112 → 188
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    cl11397
    Location:206 → 435
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

  4. XM_012692861.4 → XP_012548315.1  protein ultraspiracle homolog isoform X1

    See identical proteins and their annotated locations for XP_012548315.1

    UniProtKB/TrEMBL
    A0A8R2G9S5
    Conserved Domains (2) summary
    cd06956
    Location:112 → 188
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    cl11397
    Location:206 → 435
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

  5. XM_062677084.1 → XP_062533068.1  protein ultraspiracle homolog isoform X1

    UniProtKB/TrEMBL
    A0A8R2G9S5

  6. XM_062677088.1 → XP_062533072.1  protein ultraspiracle homolog isoform X1

    UniProtKB/TrEMBL
    A0A8R2G9S5

  7. XM_012692862.4 → XP_012548316.1  protein ultraspiracle homolog isoform X1

    See identical proteins and their annotated locations for XP_012548316.1

    UniProtKB/TrEMBL
    A0A8R2G9S5
    Conserved Domains (2) summary
    cd06956
    Location:112 → 188
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    cl11397
    Location:206 → 435
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

  8. XM_062677085.1 → XP_062533069.1  protein ultraspiracle homolog isoform X1

    UniProtKB/TrEMBL
    A0A8R2G9S5

  9. XM_062677087.1 → XP_062533071.1  protein ultraspiracle homolog isoform X1

    UniProtKB/TrEMBL
    A0A8R2G9S5

  10. XM_012692859.4 → XP_012548313.1  protein ultraspiracle homolog isoform X1

    See identical proteins and their annotated locations for XP_012548313.1

    UniProtKB/TrEMBL
    A0A8R2G9S5
    Conserved Domains (2) summary
    cd06956
    Location:112 → 188
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    cl11397
    Location:206 → 435
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

  11. XM_021349878.3 → XP_021205553.1  protein ultraspiracle homolog isoform X1

    UniProtKB/TrEMBL
    A0A8R2G9S5
    Conserved Domains (2) summary
    cd06956
    Location:112 → 188
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    cl11397
    Location:206 → 435
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

  12. XM_062677086.1 → XP_062533070.1  protein ultraspiracle homolog isoform X1

    UniProtKB/TrEMBL
    A0A8R2G9S5

  13. XM_062677089.1 → XP_062533073.1  protein ultraspiracle homolog isoform X1

    UniProtKB/TrEMBL
    A0A8R2G9S5
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P49700.1 GenPept UniProtKB/Swiss-Prot:P49700

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