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Ccdc166 coiled-coil domain containing 166 [ Rattus norvegicus (Norway rat) ]

Gene ID: 680799, updated on 17-Aug-2024

Summary

Official Symbol
Ccdc166provided by RGD
Official Full Name
coiled-coil domain containing 166provided by RGD
Primary source
RGD:1588167
See related
EnsemblRapid:ENSRNOG00000047521 AllianceGenome:RGD:1588167
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Orthologous to human CCDC166 (coiled-coil domain containing 166). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 37.8) and Brain (RPKM 4.2) See more
Orthologs
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Genomic context

Location:
7q34
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (109574271..109576074, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (107693572..107695375, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (117039890..117041693, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120093815 Neighboring gene zinc finger protein 707-like 1 Neighboring gene zinc finger protein 707 Neighboring gene mitogen-activated protein kinase 15 Neighboring gene family with sequence similarity 83, member H Neighboring gene IQ motif and ankyrin repeat containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
coiled-coil domain-containing protein 166

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130509.2NP_001123981.2  coiled-coil domain-containing protein 166 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript but encodes the longer isoform (1).
    Source sequence(s)
    BC160829
    UniProtKB/TrEMBL
    M0R4R5
    Related
    ENSRNOP00000064360.2, ENSRNOT00000073835.4
    Conserved Domains (3) summary
    pfam03035
    Location:309394
    RNA_capsid; Calicivirus putative RNA polymerase/capsid protein
    pfam14988
    Location:69255
    DUF4515; Domain of unknown function (DUF4515)
    cl19252
    Location:206254
    MreC; rod shape-determining protein MreC
  2. NM_001163519.1NP_001156991.1  coiled-coil domain-containing protein 166 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) retains an intron resulting in a frameshift, compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    BC160829
    Conserved Domains (1) summary
    pfam14988
    Location:69145
    DUF4515; Domain of unknown function (DUF4515)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    109574271..109576074 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)