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aPKC protein kinase C iota type [ Drosophila simulans ]

Gene ID: 6734568, updated on 16-May-2024

Summary

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Gene symbol
aPKC
Gene description
protein kinase C iota type
Locus tag
Dsimw501_GD25642
See related
EnsemblRapid:LOC6734568
Gene type
protein coding
RefSeq status
MODEL
Organism
Drosophila simulans
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
GD25642; GD25642-PB; GD25642-PC; GD25642-PD; GD25642-PE; GD25642-PF; GD25642-PG; GD25642-PH; GD25642-PI; GD25642-PJ; GD25642-PK
Orthologs
fruit fly all
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Genomic context

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See aPKC in Genome Data Viewer
Location:
chromosome: 2R
Exon count:
17
Annotation release Status Assembly Chr Location
103 current Prin_Dsim_3.1 (GCF_016746395.2) 2R NC_052521.2 (12214170..12232789, complement)
102 previous assembly Prin_Dsim_3.0 (GCF_016746395.1) 2R NC_052521.1 (12214306..12232789, complement)

Chromosome 2R - NC_052521.2Genomic Context describing neighboring genes Neighboring gene protein lap1 Neighboring gene fas apoptotic inhibitory molecule 1 Neighboring gene CRK like proto-oncogene, adaptor protein Neighboring gene uncharacterized LOC120284465 Neighboring gene SH3 domain-binding protein 5 homolog Neighboring gene transfer RNA leucine (anticodon AAG)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolution of genes and genomes on the Drosophila phylogeny. Drosophila 12 Genomes Consortium, et al. Nature, 2007 Nov 8. PMID 17994087

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in establishment or maintenance of cell polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
atypical protein kinase C
Names
Dsim\GD25642
Dsim\GD25642-PB
Dsim\GD25642-PC
Dsim\GD25642-PD
Dsim\GD25642-PE
Dsim\GD25642-PF
Dsim\GD25642-PG
Dsim\GD25642-PH
Dsim\GD25642-PI
Dsim\GD25642-PJ
Dsim\GD25642-PK
dsim_GLEANR_9632

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Drosophila simulans Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Prin_Dsim_3.1

Genomic

  1. NC_052521.2 Reference Prin_Dsim_3.1

    Range
    12214170..12232789 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016181963.3 → XP_016027685.1  atypical protein kinase C isoform X4

    UniProtKB/TrEMBL
    A0A0J9U2B4, B4QGC4
    Related
    XP_016027685.1, XM_016181963.3
    Conserved Domains (3) summary
    cd06404
    Location:31 → 113
    PB1_aPKC; PB1 domain is an essential modular domain of the atypical protein kinase C (aPKC) which in complex with Par6 and Par3 proteins is crucial for establishment of apical-basal polarity of animal cells. PB1 domain is a modular domain mediating specific ...
    cd05588
    Location:268 → 597
    STKc_aPKC; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C
    cd20794
    Location:144 → 198
    C1_aPKC; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) family

  2. XM_016181965.3 → XP_016027687.1  atypical protein kinase C isoform X5

    UniProtKB/TrEMBL
    A0A0J9RD09, B4QGC4
    Related
    XP_016027687.1, XM_016181965.3
    Conserved Domains (3) summary
    cd06404
    Location:31 → 113
    PB1_aPKC; PB1 domain is an essential modular domain of the atypical protein kinase C (aPKC) which in complex with Par6 and Par3 proteins is crucial for establishment of apical-basal polarity of animal cells. PB1 domain is a modular domain mediating specific ...
    cd05588
    Location:268 → 595
    STKc_aPKC; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C
    cd20794
    Location:144 → 198
    C1_aPKC; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) family

  3. XM_039292783.2 → XP_039148717.1  atypical protein kinase C isoform X1

    UniProtKB/TrEMBL
    A0A0J9RD05, A0A0J9U2C1
    Related
    XP_039148717.1, XM_039292783.2
    Conserved Domains (2) summary
    cd05588
    Location:623 → 952
    STKc_aPKC; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C
    cd20794
    Location:499 → 553
    C1_aPKC; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) family

  4. XM_016181961.3 → XP_016027683.1  atypical protein kinase C isoform X3

    UniProtKB/TrEMBL
    A0A0J9RCU8, A0A0J9U2C1
    Related
    XP_016027683.1, XM_016181961.3
    Conserved Domains (3) summary
    smart00220
    Location:612 → 880
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd05588
    Location:616 → 943
    STKc_aPKC; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C
    pfam00130
    Location:494 → 546
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  5. XM_016181964.3 → XP_016027686.1  atypical protein kinase C isoform X2

    UniProtKB/TrEMBL
    A0A0J9RD44, A0A0J9U2C1
    Related
    XP_016027686.1, XM_016181964.3
    Conserved Domains (3) summary
    smart00220
    Location:619 → 887
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd05588
    Location:623 → 950
    STKc_aPKC; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C
    pfam00130
    Location:501 → 553
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  6. XM_016181967.3 → XP_016027689.1  atypical protein kinase C isoform X6

    UniProtKB/TrEMBL
    A0A0J9RE75, B4QGC4
    Related
    XP_016027689.1, XM_016181967.3
    Conserved Domains (2) summary
    cd05588
    Location:186 → 515
    STKc_aPKC; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C
    cd20794
    Location:62 → 116
    C1_aPKC; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) family

  7. XM_016181966.3 → XP_016027688.1  atypical protein kinase C isoform X7

    UniProtKB/TrEMBL
    A0A0J9RCV4, B4QGC4
    Related
    XP_016027688.1, XM_016181966.3
    Conserved Domains (2) summary
    cd05588
    Location:186 → 513
    STKc_aPKC; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C
    cd20794
    Location:62 → 116
    C1_aPKC; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) family

  8. XM_039292787.2 → XP_039148721.1  atypical protein kinase C isoform X8

    UniProtKB/TrEMBL
    B4QGC4
    Related
    XP_039148721.1, XM_039292787.2
    Conserved Domains (2) summary
    cd05588
    Location:180 → 507
    STKc_aPKC; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C
    cd20794
    Location:56 → 110
    C1_aPKC; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) family
Nucleotide Protein Strain
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