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MCU mitochondrial calcium uniporter [ Drosophila willistoni ]

Gene ID: 6645051, updated on 24-May-2024

Summary

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Gene symbol
MCU
Gene description
mitochondrial calcium uniporter
Locus tag
Dwil_GK12545
See related
EnsemblRapid:LOC6645051
Gene type
protein coding
RefSeq status
MODEL
Organism
Drosophila willistoni
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
GK12545; GK26860; GK27527; GK12545-PA; GK26860-PA; GK27527-PA
Orthologs
fruit fly all
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Genomic context

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See MCU in Genome Data Viewer
Location:
chromosome: XR
Exon count:
10
Annotation release Status Assembly Chr Location
102 current UCI_dwil_1.1 (GCF_018902025.1) XR Unlocalized Scaffold NW_025814054.1 (757605..817939, complement)
101 previous assembly dwil_caf1 (GCF_000005925.1) Unplaced Scaffold NW_002032683.1 (792183..852491, complement)

NW_025814054.1Genomic Context describing neighboring genes Neighboring gene RNA exonuclease 5 Neighboring gene zero population growth Neighboring gene serine protease nudel Neighboring gene protein javelin Neighboring gene N-deacetylase and N-sulfotransferase sfl Neighboring gene uncharacterized LOC124460594 Neighboring gene uncharacterized LOC111518942

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolution of genes and genomes on the Drosophila phylogeny. Drosophila 12 Genomes Consortium, et al. Nature, 2007 Nov 8. PMID 17994087

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables uniporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium import into the mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitochondrial calcium ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of uniplex complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calcium uniporter protein, mitochondrial
Names
Dwil\GK12545
Dwil\GK12545-PA
Dwil\GK26860
Dwil\GK26860-PA
Dwil\GK27527
Dwil\GK27527-PA
dwil_GLEANR_12847

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Drosophila willistoni Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCI_dwil_1.1

Genomic

  1. NW_025814054.1 Reference UCI_dwil_1.1

    Range
    757605..817939 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023177148.2 → XP_023032916.1  calcium uniporter protein, mitochondrial isoform X3

    Related
    XP_023032916.1, XM_023177148.2
    Conserved Domains (1) summary
    pfam04678
    Location:131 → 333
    MCU; Mitochondrial calcium uniporter

  2. XM_047011766.1 → XP_046867722.1  calcium uniporter protein, mitochondrial isoform X1

    Related
    XP_046867722.1, XM_047011766.1

  3. XM_047011767.1 → XP_046867723.1  calcium uniporter protein, mitochondrial isoform X2

    Related
    XP_046867723.1, XM_047011767.1
Nucleotide Protein
Heading Accession and Version

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