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Top3beta Topoisomerase 3beta [ Tribolium castaneum (red flour beetle) ]

Gene ID: 664404, updated on 10-May-2024

Summary

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Gene symbol
Top3beta
Gene description
Topoisomerase 3beta
Locus tag
TcasGA2_TC007344
Gene type
protein coding
RefSeq status
MODEL
Organism
Tribolium castaneum
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia; Tenebrionidae; Tenebrionidae incertae sedis; Tribolium
Orthologs
fruit fly all
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Genomic context

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See Top3beta in Genome Data Viewer
Location:
chromosome: 9
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_04 current icTriCast1.1 (GCF_031307605.1) 9 NC_087402.1 (6023039..6028314, complement)
103 previous assembly Tcas5.2 (GCF_000002335.3) Linkage Group LG4 NC_007419.2 (5871397..5876646, complement)

Chromosome 9 - NC_087402.1Genomic Context describing neighboring genes Neighboring gene protein bric-a-brac 1 Neighboring gene fire dancer Neighboring gene double-stranded RNA-binding protein Staufen homolog Neighboring gene rickets Neighboring gene uncharacterized LOC107397805

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. BeetleBase in 2010: revisions to provide comprehensive genomic information for Tribolium castaneum. Kim HS, et al. Nucleic Acids Res, 2010 Jan. PMID 19820115, Free PMC Article
  2. The genome of the model beetle and pest Tribolium castaneum. Tribolium Genome Sequencing Consortium, et al. Nature, 2008 Apr 24. PMID 18362917

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA topoisomerase type I (single strand cut, ATP-independent) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA topological change IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA topoisomerase 3-beta-1
Names
AUGUSTUS-3.0.2_07344
DNA topoisomerase 3-beta-like Protein
GLEAN_07344

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_031307605.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference icTriCast1.1 Primary Assembly

Genomic

  1. NC_087402.1 Reference icTriCast1.1 Primary Assembly

    Range
    6023039..6028314 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_970411.4 → XP_975504.1  DNA topoisomerase 3-beta-1

    See identical proteins and their annotated locations for XP_975504.1

    UniProtKB/TrEMBL
    D2A047
    Conserved Domains (3) summary
    cd03362
    Location:6 → 166
    TOPRIM_TopoIA_TopoIII; TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving ...
    PRK07219
    Location:7 → 785
    PRK07219; DNA topoisomerase I; Validated
    cd00186
    Location:171 → 592
    TOP1Ac; DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA ...
Nucleotide Protein Strain
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