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Usp8 Ubiquitin specific protease 8 [ Drosophila mojavensis ]

Gene ID: 6574216, updated on 22-May-2024

Summary

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Gene symbol
Usp8
Gene description
Ubiquitin specific protease 8
Locus tag
Dmoj_GI10137
See related
EnsemblRapid:LOC6574216
Gene type
protein coding
RefSeq status
MODEL
Organism
Drosophila mojavensis
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila
Also known as
GI10137; GI10137-PA; GI10137-PB; GI10137-PC
Orthologs
fruit fly all
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Genomic context

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Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
102 current ASM1815372v1 (GCF_018153725.1) Unplaced Scaffold NW_025318822.1 (3356303..3360624)
101 previous assembly dmoj_caf1 (GCF_000005175.2) Unplaced Scaffold NW_001979112.1 (21904888..21909204)

NW_025318822.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC6574210 Neighboring gene uncharacterized LOC6574211 Neighboring gene antichymotrypsin-2 Neighboring gene SNF4/AMP-activated protein kinase gamma subunit Neighboring gene Solute carrier family 35 member B1 homolog meigo Neighboring gene Common Dpr-interacting protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolution of genes and genomes on the Drosophila phylogeny. Drosophila 12 Genomes Consortium, et al. Nature, 2007 Nov 8. PMID 17994087

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ubiquitin carboxyl-terminal hydrolase 8
Names
Dmoj\GI10137
Dmoj\GI10137-PA
Dmoj\GI10137-PB
Dmoj\GI10137-PC
dmoj_GLEANR_10090

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Drosophila mojavensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1815372v1

Genomic

  1. NW_025318822.1 Reference ASM1815372v1

    Range
    3356303..3360624
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015167322.3 → XP_015022808.1  ubiquitin carboxyl-terminal hydrolase 8 isoform X1

    UniProtKB/TrEMBL
    B4KB31
    Related
    XP_015022808.1, XM_015167322.3
    Conserved Domains (4) summary
    pfam00443
    Location:574 → 897
    UCH; Ubiquitin carboxyl-terminal hydrolase
    pfam04880
    Location:421 → 563
    NUDE_C; NUDE protein, C-terminal conserved region
    pfam08969
    Location:2 → 113
    USP8_dimer; USP8 dimerization domain
    cl00125
    Location:154 → 284
    RHOD; Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins ...

  2. XM_044008410.1 → XP_043864345.1  ubiquitin carboxyl-terminal hydrolase 8 isoform X1

    UniProtKB/TrEMBL
    B4KB31
    Related
    XP_043864345.1, XM_044008410.1
    Conserved Domains (4) summary
    pfam00443
    Location:574 → 897
    UCH; Ubiquitin carboxyl-terminal hydrolase
    pfam04880
    Location:421 → 563
    NUDE_C; NUDE protein, C-terminal conserved region
    pfam08969
    Location:2 → 113
    USP8_dimer; USP8 dimerization domain
    cl00125
    Location:154 → 284
    RHOD; Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins ...

  3. XM_015167323.3 → XP_015022809.1  ubiquitin carboxyl-terminal hydrolase 8 isoform X2

    UniProtKB/TrEMBL
    A0A0Q9XBI2
    Related
    XP_015022809.1, XM_015167323.3
    Conserved Domains (2) summary
    cd02674
    Location:32 → 355
    Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam00443
    Location:30 → 354
    UCH; Ubiquitin carboxyl-terminal hydrolase
Nucleotide Protein
Heading Accession and Version

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