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Npc2a Niemann-Pick type C-2a [ Drosophila erecta ]

Gene ID: 6542017, updated on 22-May-2024

Summary

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Gene symbol
Npc2a
Gene description
Niemann-Pick type C-2a
Locus tag
Dere_GG24820
See related
EnsemblRapid:LOC6542017
Gene type
protein coding
RefSeq status
MODEL
Organism
Drosophila erecta
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
GG24820; GG24820-PA
Orthologs
fruit fly all
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Genomic context

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See Npc2a in Genome Data Viewer
Location:
chromosome: Un
Exon count:
1
Annotation release Status Assembly Chr Location
101 current DereRS2 (GCF_003286155.1) Unplaced Scaffold NW_020825200.1 (2154068..2154819)

NW_020825200.1Genomic Context describing neighboring genes Neighboring gene histidine triad nucleotide-binding protein 3 Neighboring gene uncharacterized protein KIAA2013 homolog Neighboring gene glutamate oxaloacetate transaminase 2 Neighboring gene Odorant-binding protein 22a Neighboring gene neural cell adhesion molecule 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020825200 Unplaced Scaffold Reference DereRS2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolution of genes and genomes on the Drosophila phylogeny. Drosophila 12 Genomes Consortium, et al. Nature, 2007 Nov 8. PMID 17994087

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables sterol binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular cholesterol transport IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NPC intracellular cholesterol transporter 2 homolog a
Names
Dere\GG24820
Dere\GG24820-PA
dere_GLEANR_9511

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Drosophila erecta Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference DereRS2

Genomic

  1. NW_020825200.1 Reference DereRS2

    Range
    2154068..2154819
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001968304.3 → XP_001968340.1  NPC intracellular cholesterol transporter 2 homolog a

    See identical proteins and their annotated locations for XP_001968340.1

    UniProtKB/TrEMBL
    B3N8Z9
    Related
    XP_001968340.1, XM_001968304.3
    Conserved Domains (1) summary
    cd00916
    Location:21 → 145
    Npc2_like; Niemann-Pick type C2 (Npc2) is a lysosomal protein in which a mutation in the gene causes a rare form of Niemann-Pick type C disease, an autosomal recessive lipid storage disorder characterized by accumulation of low-density lipoprotein-derived ...
Nucleotide Protein
Heading Accession and Version

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