nox4 NADPH oxidase 4 [Ciona intestinalis (vase tunicate)] - Gene

Summary

Gene symbol: nox4
Gene description: NADPH oxidase 4
See related: Ensembl:ENSCING00000007824
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Ciona intestinalis
Lineage: Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia; Cionidae; Ciona
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 6

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
104	current	KH (GCF_000224145.3)	6	NC_020171.2 (586792..603227, complement)

Chromosome 6 - NC_020171.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_020171.2 Chromosome 6 Reference KH Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables superoxide-generating NAD(P)H oxidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in defense response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in superoxide anion generation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of NADPH oxidase complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: NADPH oxidase 4

NP_001029001.1

EC 1.6.3.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001033829.1 → NP_001029001.1 NADPH oxidase 4

See identical proteins and their annotated locations for NP_001029001.1

Status: PROVISIONAL

Source sequence(s)

AB196472

UniProtKB/TrEMBL

A0A1W2VNN5, F6YS00, Q4R1Q7

Related

ENSCINP00000026729, ENSCINT00000026975

Conserved Domains (3) summary

cd06186
Location:619 → 811

NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...

pfam01794
Location:59 → 202

Ferric_reduct; Ferric reductase like transmembrane component

cl06868
Location:382 → 446

FNR_like; Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport ...