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FERMT2 FERM domain containing kindlin 2 [ Bos taurus (cattle) ]

Gene ID: 616981, updated on 6-Jun-2024

Summary

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Official Symbol
FERMT2provided by VGNC
Official Full Name
FERM domain containing kindlin 2provided by VGNC
Primary source
VGNC:VGNC:28953
See related
BGD:BT17420; Ensembl:ENSBTAG00000014501
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See FERMT2 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (65537744..65614911, complement)

Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial-like Neighboring gene transfer RNA serine (anticodon GGA) Neighboring gene putative histone H2B type 2-D Neighboring gene DDHD domain containing 1 Neighboring gene small nucleolar RNA U3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fermitin family homolog 2
Names
fermitin family member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001101264.1 → NP_001094734.1  fermitin family homolog 2

    See identical proteins and their annotated locations for NP_001094734.1

    Status: PROVISIONAL

    Source sequence(s)
    BC151292
    UniProtKB/TrEMBL
    A7MB21
    Related
    ENSBTAP00000019278.4, ENSBTAT00000019278.5
    Conserved Domains (6) summary
    smart00295
    Location:241 → 324
    B41; Band 4.1 homologues
    cd01237
    Location:373 → 497
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:567 → 658
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:17 → 96
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:97 → 277
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)
    pfam00373
    Location:484 → 573
    FERM_M; FERM central domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    65537744..65614911 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024997834.2 → XP_024853602.1  fermitin family homolog 2 isoform X6

    UniProtKB/TrEMBL
    A7MB21
    Conserved Domains (6) summary
    smart00295
    Location:241 → 324
    B41; Band 4.1 homologues
    cd01237
    Location:373 → 497
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:567 → 658
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:17 → 96
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:97 → 277
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)
    pfam00373
    Location:484 → 573
    FERM_M; FERM central domain

  2. XM_010809381.3 → XP_010807683.1  fermitin family homolog 2 isoform X1

    See identical proteins and their annotated locations for XP_010807683.1

    Conserved Domains (6) summary
    smart00295
    Location:252 → 335
    B41; Band 4.1 homologues
    cd01237
    Location:384 → 508
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:593 → 684
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:17 → 96
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:97 → 288
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)
    pfam00373
    Location:526 → 599
    FERM_M; FERM central domain

  3. XM_005211866.5 → XP_005211923.1  fermitin family homolog 2 isoform X5

    See identical proteins and their annotated locations for XP_005211923.1

    UniProtKB/TrEMBL
    A0AAA9S7V5
    Related
    ENSBTAP00000078224.1, ENSBTAT00000089364.1
    Conserved Domains (6) summary
    smart00295
    Location:241 → 324
    B41; Band 4.1 homologues
    cd01237
    Location:373 → 497
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:574 → 665
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:17 → 96
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:97 → 277
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)
    pfam00373
    Location:484 → 580
    FERM_M; FERM central domain

  4. XM_005211864.5 → XP_005211921.1  fermitin family homolog 2 isoform X3

    See identical proteins and their annotated locations for XP_005211921.1

    Conserved Domains (6) summary
    smart00295
    Location:241 → 324
    B41; Band 4.1 homologues
    cd01237
    Location:373 → 497
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:582 → 673
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:17 → 96
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:97 → 277
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)
    pfam00373
    Location:515 → 588
    FERM_M; FERM central domain

  5. XM_005211865.5 → XP_005211922.1  fermitin family homolog 2 isoform X4

    See identical proteins and their annotated locations for XP_005211922.1

    Conserved Domains (6) summary
    smart00295
    Location:252 → 335
    B41; Band 4.1 homologues
    cd01237
    Location:384 → 508
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:578 → 669
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:17 → 96
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:97 → 288
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)
    pfam00373
    Location:495 → 584
    FERM_M; FERM central domain

  6. XM_005211863.5 → XP_005211920.1  fermitin family homolog 2 isoform X2

    See identical proteins and their annotated locations for XP_005211920.1

    Conserved Domains (6) summary
    smart00295
    Location:252 → 335
    B41; Band 4.1 homologues
    cd01237
    Location:384 → 508
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:585 → 676
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:17 → 96
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:97 → 288
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)
    pfam00373
    Location:495 → 591
    FERM_M; FERM central domain

  7. XM_005211862.5 → XP_005211919.1  fermitin family homolog 2 isoform X1

    See identical proteins and their annotated locations for XP_005211919.1

    Conserved Domains (6) summary
    smart00295
    Location:252 → 335
    B41; Band 4.1 homologues
    cd01237
    Location:384 → 508
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:593 → 684
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:17 → 96
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:97 → 288
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)
    pfam00373
    Location:526 → 599
    FERM_M; FERM central domain
Nucleotide Protein Strain
Heading Accession and Version

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