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SH2B3 SH2B adaptor protein 3 [ Bos taurus (cattle) ]

Gene ID: 614726, updated on 5-Mar-2024

Summary

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Official Symbol
SH2B3provided by VGNC
Official Full Name
SH2B adaptor protein 3provided by VGNC
Primary source
VGNC:VGNC:34556
See related
BGD:BT15012; Ensembl:ENSBTAG00000009101
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See SH2B3 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 17 NC_037344.1 (55140779..55178298)

Chromosome 17 - NC_037344.1Genomic Context describing neighboring genes Neighboring gene myosin light chain 2 Neighboring gene cut like homeobox 2 Neighboring gene PH domain containing endocytic trafficking adaptor 1 Neighboring gene E3 SUMO-protein ligase NSE2-like Neighboring gene ataxin 2 Neighboring gene acyl-CoA dehydrogenase family member 10 Neighboring gene transfer RNA glutamic acid (anticodon CUC)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables transmembrane receptor protein tyrosine kinase adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SH2B adapter protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001193067.2 → NP_001179996.2  SH2B adapter protein 3

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000017
    UniProtKB/TrEMBL
    E1BE90
    Conserved Domains (3) summary
    cd10412
    Location:374 → 470
    SH2_SH2B3; Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)
    cd01231
    Location:213 → 327
    PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
    pfam08916
    Location:29 → 84
    Phe_ZIP; Phenylalanine zipper

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037344.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    55140779..55178298
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059876156.1 → XP_059732139.1  SH2B adapter protein 3 isoform X1

  2. XM_059876157.1 → XP_059732140.1  SH2B adapter protein 3 isoform X4

  3. XM_024977441.2 → XP_024833209.1  SH2B adapter protein 3 isoform X2

    Related
    ENSBTAP00000071601.2, ENSBTAT00000079236.2
    Conserved Domains (3) summary
    cd10412
    Location:381 → 477
    SH2_SH2B3; Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)
    cd01231
    Location:213 → 334
    PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
    pfam08916
    Location:29 → 84
    Phe_ZIP; Phenylalanine zipper

  4. XM_024977443.2 → XP_024833211.1  SH2B adapter protein 3 isoform X3

    UniProtKB/TrEMBL
    A0A3Q1MQG1
    Conserved Domains (3) summary
    cd10412
    Location:374 → 470
    SH2_SH2B3; Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)
    cd01231
    Location:213 → 327
    PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
    pfam08916
    Location:29 → 84
    Phe_ZIP; Phenylalanine zipper

  5. XM_005217911.5 → XP_005217968.2  SH2B adapter protein 3 isoform X5

    UniProtKB/TrEMBL
    E1BE90
    Related
    ENSBTAP00000029616.5, ENSBTAT00000029618.6
    Conserved Domains (3) summary
    cd10412
    Location:374 → 470
    SH2_SH2B3; Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)
    cd01231
    Location:213 → 327
    PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
    pfam08916
    Location:29 → 84
    Phe_ZIP; Phenylalanine zipper
Nucleotide Protein Strain
Heading Accession and Version

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