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FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) [ Sus scrofa (pig) ]

Gene ID: 613131, updated on 16-Nov-2023

Summary

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Gene symbol
FCGR2B
Gene description
Fc fragment of IgG, low affinity IIb, receptor (CD32)
See related
Ensembl:ENSSSCG00000006350
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
CD32
Expression
Broad expression in liver (RPKM 29.9), subcutaneous adipose (RPKM 17.4) and 8 other tissues See more
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Genomic context

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Location:
chromosome: 4
Exon count:
10
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 4 NC_010446.5 (88873762..88892964, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 4 NC_010446.4 (96889007..96908224, complement)

Chromosome 4 - NC_010446.5Genomic Context describing neighboring genes Neighboring gene Fc receptor like B Neighboring gene Fc receptor like A Neighboring gene Fc fragment of IgG receptor IIIa Neighboring gene transfer RNA asparagine (anticodon GUU)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Porcine FcγRIIb mediates enhancement of porcine reproductive and respiratory syndrome virus (PRRSV) infection. Qiao S, et al. PLoS One, 2011. PMID 22220194, Free PMC Article
  2. Cloning and characterization of porcine Fc gamma receptor II (FcgammaRII). Qiao S, et al. Vet Immunol Immunopathol, 2006 Nov 15. PMID 16930721
  3. Activation of Fc gamma receptor IIb up-regulates the production of interferon-alpha and interferon-gamma in porcine alveolar macrophages during PRRSV infection. Zhang L, et al. Dev Comp Immunol, 2020 Aug. PMID 32278861
  4. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Activation of Fc gamma receptor IIb up-regulates the production of interferon-alpha and interferon-gamma in porcine alveolar macrophages during PRRSV infection.
    Title: Activation of Fc gamma receptor IIb up-regulates the production of interferon-alpha and interferon-gamma in porcine alveolar macrophages during PRRSV infection.
  2. These results indicate that enhancement of infection by anti-porcine reproductive and respiratory syndrome virus antibody is FcgammaRII-mediated.
    Title: Porcine FcγRIIb mediates enhancement of porcine reproductive and respiratory syndrome virus (PRRSV) infection.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
low affinity immunoglobulin gamma Fc region receptor II-b
Names
Fc gamma receptor II

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033013.2 → NP_001028185.1  low affinity immunoglobulin gamma Fc region receptor II-b precursor

    See identical proteins and their annotated locations for NP_001028185.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ026064
    UniProtKB/TrEMBL
    A0A8D0UE53, Q461P7
    Related
    ENSSSCP00000031051.3, ENSSSCT00000033848.4
    Conserved Domains (3) summary
    cd05753
    Location:132 → 214
    Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins
    smart00410
    Location:138 → 214
    IG_like; Immunoglobulin like
    cl11960
    Location:50 → 128
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010446.5 Reference Sscrofa11.1 Primary Assembly

    Range
    88873762..88892964 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013996820.2 → XP_013852274.1  low affinity immunoglobulin gamma Fc region receptor II-b isoform X7

    Conserved Domains (2) summary
    cd05753
    Location:46 → 128
    Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins
    smart00410
    Location:52 → 128
    IG_like; Immunoglobulin like

  2. XM_021088750.1 → XP_020944409.1  low affinity immunoglobulin gamma Fc region receptor II-b isoform X2

    UniProtKB/TrEMBL
    A0A8D0JAS7
    Conserved Domains (2) summary
    cd05753
    Location:131 → 213
    Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins
    cl11960
    Location:49 → 127
    Ig; Immunoglobulin domain

  3. XM_005663158.3 → XP_005663215.1  low affinity immunoglobulin gamma Fc region receptor II-b isoform X5

    See identical proteins and their annotated locations for XP_005663215.1

    UniProtKB/TrEMBL
    A0A8D0JJN5, A0A8D0Q928, D0FH22
    Conserved Domains (3) summary
    cd05753
    Location:131 → 213
    Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins
    smart00410
    Location:137 → 213
    IG_like; Immunoglobulin like
    cl11960
    Location:49 → 127
    Ig; Immunoglobulin domain

  4. XM_013996818.2 → XP_013852272.1  low affinity immunoglobulin gamma Fc region receptor II-b isoform X1

    UniProtKB/TrEMBL
    A0A8D0JAS7
    Conserved Domains (3) summary
    cd05753
    Location:132 → 214
    Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins
    smart00410
    Location:138 → 214
    IG_like; Immunoglobulin like
    cl11960
    Location:50 → 128
    Ig; Immunoglobulin domain

  5. XM_005663159.3 → XP_005663216.1  low affinity immunoglobulin gamma Fc region receptor II-b isoform X6

    See identical proteins and their annotated locations for XP_005663216.1

    UniProtKB/TrEMBL
    A0A0B4J2J8, A0A0B4J2K0, A0A8D1PX08, E5G9H5
    Conserved Domains (3) summary
    cd05753
    Location:131 → 213
    Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins
    smart00410
    Location:137 → 213
    IG_like; Immunoglobulin like
    cl11960
    Location:49 → 127
    Ig; Immunoglobulin domain

  6. XM_005663157.3 → XP_005663214.1  low affinity immunoglobulin gamma Fc region receptor II-b isoform X3

    UniProtKB/TrEMBL
    A0A8D0JJN5, A0A8D0Q928, A0A8D1J743, A0A8X9AEV4
    Related
    ENSSSCP00000006770.4, ENSSSCT00000006959.6
    Conserved Domains (3) summary
    cd05753
    Location:132 → 214
    Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins
    smart00410
    Location:138 → 214
    IG_like; Immunoglobulin like
    cl11960
    Location:50 → 128
    Ig; Immunoglobulin domain

  7. XM_013996819.2 → XP_013852273.1  low affinity immunoglobulin gamma Fc region receptor II-b isoform X4

    UniProtKB/TrEMBL
    A0A8D0LNZ2, A0A8D1BL54, A0A8D1YLS5, A0A8X9AES6
    Related
    ENSSSCP00000029706.4, ENSSSCT00000033401.4
    Conserved Domains (3) summary
    cd05753
    Location:132 → 214
    Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins
    smart00410
    Location:138 → 214
    IG_like; Immunoglobulin like
    cl11960
    Location:50 → 128
    Ig; Immunoglobulin domain

RNA

  1. XR_001308300.2 RNA Sequence

  2. XR_001308301.2 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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