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BBC3 BCL2 binding component 3 [ Canis lupus familiaris (dog) ]

Gene ID: 612153, updated on 5-Mar-2024

Summary

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Official Symbol
BBC3provided by VGNC
Official Full Name
BCL2 binding component 3provided by VGNC
Primary source
VGNC:VGNC:111360
See related
Ensembl:ENSCAFG00845002815
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See BBC3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
6
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (109267089..109276129)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (108222131..108231165)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (109447382..109456419)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (108934859..108943893)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (108578770..108587804)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 9 Neighboring gene uncharacterized LOC102156678 Neighboring gene basic proline-rich protein-like Neighboring gene SUMO1 activating enzyme subunit 1 Neighboring gene U6 spliceosomal RNA Neighboring gene zinc finger CCCH-type containing 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in execution phase of apoptosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of release of cytochrome c from mitochondria IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in release of cytochrome c from mitochondria IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bcl-2-binding component 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    109267089..109276129
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038656547.1 → XP_038512475.1  bcl-2-binding component 3

    UniProtKB/TrEMBL
    A0A8C0MK34, A0A8I3MGC5
    Related
    ENSCAFP00845003970.1, ENSCAFT00845004982.1
    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

  2. XM_038656550.1 → XP_038512478.1  bcl-2-binding component 3

    UniProtKB/TrEMBL
    A0A8C0MK34, A0A8I3MGC5
    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

  3. XM_038656548.1 → XP_038512476.1  bcl-2-binding component 3

    UniProtKB/TrEMBL
    A0A8C0MK34, A0A8I3MGC5
    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

  4. XM_038656549.1 → XP_038512477.1  bcl-2-binding component 3

    UniProtKB/TrEMBL
    A0A8C0MK34, A0A8I3MGC5
    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    108934859..108943893
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038467746.1 → XP_038323674.1  bcl-2-binding component 3

    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

  2. XM_038467749.1 → XP_038323677.1  bcl-2-binding component 3

    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

  3. XM_038467747.1 → XP_038323675.1  bcl-2-binding component 3

    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

  4. XM_038467748.1 → XP_038323676.1  bcl-2-binding component 3

    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    108578770..108587804
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038592754.1 → XP_038448682.1  bcl-2-binding component 3

    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

  2. XM_038592757.1 → XP_038448685.1  bcl-2-binding component 3

    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

  3. XM_038592755.1 → XP_038448683.1  bcl-2-binding component 3

    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

  4. XM_038592756.1 → XP_038448684.1  bcl-2-binding component 3

    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    109447382..109456419
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038528463.1 → XP_038384391.1  bcl-2-binding component 3

    UniProtKB/TrEMBL
    A0A8C0MK34, A0A8I3MGC5
    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

  2. XM_038528467.1 → XP_038384395.1  bcl-2-binding component 3

    UniProtKB/TrEMBL
    A0A8C0MK34, A0A8I3MGC5
    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

  3. XM_038528464.1 → XP_038384392.1  bcl-2-binding component 3

    UniProtKB/TrEMBL
    A0A8C0MK34, A0A8I3MGC5
    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

  4. XM_038528466.1 → XP_038384394.1  bcl-2-binding component 3

    UniProtKB/TrEMBL
    A0A8C0MK34, A0A8I3MGC5
    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    108222131..108231165
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038687975.1 → XP_038543903.1  bcl-2-binding component 3

    UniProtKB/TrEMBL
    A0A8C0MK34, A0A8I3MGC5
    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

  2. XM_849883.6 → XP_854976.1  bcl-2-binding component 3

    See identical proteins and their annotated locations for XP_854976.1

    UniProtKB/TrEMBL
    A0A8C0MK34, A0A8I3MGC5
    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

  3. XM_005616403.4 → XP_005616460.1  bcl-2-binding component 3

    See identical proteins and their annotated locations for XP_005616460.1

    UniProtKB/TrEMBL
    A0A8C0MK34, A0A8I3MGC5
    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis

  4. XM_022424594.2 → XP_022280302.1  bcl-2-binding component 3

    UniProtKB/TrEMBL
    A0A8C0MK34, A0A8I3MGC5
    Conserved Domains (1) summary
    pfam15826
    Location:2 → 193
    PUMA; Bcl-2-binding component 3, p53 upregulated modulator of apoptosis
Nucleotide Protein
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