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SC5D sterol-C5-desaturase [ Canis lupus familiaris (dog) ]

Gene ID: 610411, updated on 17-Aug-2024

Summary

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Official Symbol
SC5Dprovided by VGNC
Official Full Name
sterol-C5-desaturaseprovided by VGNC
Primary source
VGNC:VGNC:45887
See related
Ensembl:ENSCAFG00845013494
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
SC5DL
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
6
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (12708566..12724659, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (12813437..12829449, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (12789890..12805983, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (12815057..12831074, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (12751628..12767860, complement)

Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119871795 Neighboring gene sortilin related receptor 1 Neighboring gene uncharacterized LOC119871796 Neighboring gene uncharacterized LOC102157382 Neighboring gene tectorin alpha

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cholesterol biosynthetic process via lathosterol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lathosterol oxidase
Names
sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like
XP_038330657.1
XP_038330658.1
XP_038363864.1
XP_038391800.1
XP_038391801.1
XP_038455998.1
XP_038455999.1
XP_038520538.1
XP_038520539.1
XP_853004.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051809.1 Reference ROS_Cfam_1.0

    Range
    12708566..12724659 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038664610.1 → XP_038520538.1  lathosterol oxidase

    UniProtKB/TrEMBL
    A0A8C0KCX0, A0A8C0RAL2, A0A8I3NSD3
    Related
    ENSCAFP00845018877.1, ENSCAFT00845024034.1
    Conserved Domains (1) summary
    COG3000
    Location:40 → 257
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]

  2. XM_038664611.1 → XP_038520539.1  lathosterol oxidase

    UniProtKB/TrEMBL
    A0A8C0KCX0, A0A8C0RAL2, A0A8I3NSD3
    Conserved Domains (1) summary
    COG3000
    Location:40 → 257
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049265.1 Alternate UMICH_Zoey_3.1

    Range
    12815057..12831074 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038474729.1 → XP_038330657.1  lathosterol oxidase

    Conserved Domains (1) summary
    COG3000
    Location:40 → 257
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]

  2. XM_038474730.1 → XP_038330658.1  lathosterol oxidase

    Conserved Domains (1) summary
    COG3000
    Location:40 → 257
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

    Range
    12751628..12767860 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038600070.1 → XP_038455998.1  lathosterol oxidase

    Conserved Domains (1) summary
    COG3000
    Location:40 → 257
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]

  2. XM_038600071.1 → XP_038455999.1  lathosterol oxidase

    Conserved Domains (1) summary
    COG3000
    Location:40 → 257
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

    Range
    12789890..12805983 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038535872.1 → XP_038391800.1  lathosterol oxidase

    UniProtKB/TrEMBL
    A0A8C0KCX0, A0A8C0RAL2, A0A8I3NSD3
    Conserved Domains (1) summary
    COG3000
    Location:40 → 257
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]

  2. XM_038535873.1 → XP_038391801.1  lathosterol oxidase

    UniProtKB/TrEMBL
    A0A8C0KCX0, A0A8C0RAL2, A0A8I3NSD3
    Conserved Domains (1) summary
    COG3000
    Location:40 → 257
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    12813437..12829449 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_847911.5 → XP_853004.1  lathosterol oxidase

    UniProtKB/TrEMBL
    A0A8C0KCX0, A0A8C0RAL2, A0A8I3NSD3
    Conserved Domains (1) summary
    COG3000
    Location:40 → 257
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]

  2. XM_038507936.1 → XP_038363864.1  lathosterol oxidase

    UniProtKB/TrEMBL
    A0A8C0KCX0, A0A8C0RAL2, A0A8I3NSD3
    Conserved Domains (1) summary
    COG3000
    Location:40 → 257
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]
Nucleotide Protein
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