EXOSC2 exosome component 2 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: EXOSC2provided by VGNC
Official Full Name: exosome component 2provided by VGNC
Primary source: VGNC:VGNC:40523
See related: Ensembl:ENSCAFG00845020890
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	9	NC_051813.1 (54165433..54176045, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	9	NC_006591.4 (52464948..52475561, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	9	NC_049230.1 (53356968..53367401, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	9	NC_049269.1 (52942940..52953572, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	9	NC_049750.1 (53263746..53274359, complement)

Chromosome 9 - NC_051813.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in CUT catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in TRAMP-dependent tRNA surveillance pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in U4 snRNA 3'-end processing	IEA Inferred from Electronic Annotation more info	PubMed
involved_in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IEA Inferred from Electronic Annotation more info	PubMed
involved_in nuclear polyadenylation-dependent rRNA catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in poly(A)-dependent snoRNA 3'-end processing	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of cytoplasmic exosome (RNase complex)	IEA Inferred from Electronic Annotation more info	PubMed
part_of nuclear exosome (RNase complex)	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: exosome complex exonuclease RRP4; exosome complex component RRP4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051813.1 Reference ROS_Cfam_1.0

Range

54165433..54176045 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038678278.1 → XP_038534206.1 exosome complex component RRP4

UniProtKB/TrEMBL

A0A8C0LIQ7, A0A8C0N4G7, A0A8C0ND63, A0A8I3P687, A0A8I3PF56

Related

ENSCAFP00845028877.1, ENSCAFT00845036882.1

Conserved Domains (2) summary

COG1097
Location:22 → 214

Rrp4; Exosome complex RNA-binding protein Rrp4, contains S1 and KH domains [Translation, ribosomal structure and biogenesis]

cd22525
Location:169 → 285

KH-I_Rrp4_eukar; type I K homology (KH) RNA-binding domain found in exosome complex component Rrp4 from eukaryote

Alternate UMICH_Zoey_3.1

Genomic

NC_049269.1 Alternate UMICH_Zoey_3.1

Range

52942940..52953572 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038487133.1 → XP_038343061.1 exosome complex component RRP4

Conserved Domains (2) summary

COG1097
Location:22 → 214

Rrp4; Exosome complex RNA-binding protein Rrp4, contains S1 and KH domains [Translation, ribosomal structure and biogenesis]

cd22525
Location:169 → 285

KH-I_Rrp4_eukar; type I K homology (KH) RNA-binding domain found in exosome complex component Rrp4 from eukaryote

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049750.1 Alternate UNSW_CanFamBas_1.0

Range

53263746..53274359 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038612972.1 → XP_038468900.1 exosome complex component RRP4

Conserved Domains (2) summary

COG1097
Location:22 → 214

Rrp4; Exosome complex RNA-binding protein Rrp4, contains S1 and KH domains [Translation, ribosomal structure and biogenesis]

cd22525
Location:169 → 285

KH-I_Rrp4_eukar; type I K homology (KH) RNA-binding domain found in exosome complex component Rrp4 from eukaryote

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049230.1 Alternate UU_Cfam_GSD_1.0

Range

53356968..53367401 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038549021.1 → XP_038404949.1 exosome complex component RRP4

UniProtKB/TrEMBL

A0A8C0ND63, A0A8I3PF56

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

52464948..52475561 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005625233.4 → XP_005625290.2 exosome complex component RRP4

UniProtKB/TrEMBL

A0A8C0LIQ7, A0A8C0N4G7, A0A8C0ND63, A0A8I3P687, A0A8I3PF56

Conserved Domains (2) summary

COG1097
Location:22 → 214

Rrp4; Exosome complex RNA-binding protein Rrp4, contains S1 and KH domains [Translation, ribosomal structure and biogenesis]

cd22525
Location:169 → 285

KH-I_Rrp4_eukar; type I K homology (KH) RNA-binding domain found in exosome complex component Rrp4 from eukaryote