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Graf GTPase regulator associated with FAK [ Culex quinquefasciatus (southern house mosquito) ]

Gene ID: 6050587, updated on 15-May-2024

Summary

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Gene symbol
Graf
Gene description
GTPase regulator associated with FAK
See related
VectorBase:CQUJHB003473; EnsemblRapid:LOC6050587
Gene type
protein coding
RefSeq status
MODEL
Organism
Culex quinquefasciatus
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Culicinae; Culicini; Culex; Culex
Orthologs
fruit fly all
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Genomic context

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See Graf in Genome Data Viewer
Location:
chromosome: 2
Exon count:
18
Annotation release Status Assembly Chr Location
100 current VPISU_Cqui_1.0_pri_paternal (GCF_015732765.1) 2 NC_051862.1 (98179001..98269078, complement)

Chromosome 2 - NC_051862.1Genomic Context describing neighboring genes Neighboring gene pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial Neighboring gene zinc finger protein interacting with ribonucleoprotein K Neighboring gene uncharacterized LOC6033765 Neighboring gene acidic phospholipase A2 PA4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_051862.1 Chromosome 2 Reference VPISU_Cqui_1.0_pri_paternal Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho GTPase-activating protein 26
Names
oligophrenin 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Culex quinquefasciatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VPISU_Cqui_1.0_pri_paternal Primary Assembly

Genomic

  1. NC_051862.1 Reference VPISU_Cqui_1.0_pri_paternal Primary Assembly

    Range
    98179001..98269078 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038251201.1 → XP_038107129.1  rho GTPase-activating protein 26 isoform X2

    Related
    XP_038107129.1, XM_038251201.1
    Conserved Domains (4) summary
    cd11882
    Location:913 → 965
    SH3_GRAF-like; Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase and similar proteins
    cd01249
    Location:268 → 372
    BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
    cl02570
    Location:365 → 569
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    cl12013
    Location:22 → 228
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  2. XM_038251198.1 → XP_038107126.1  rho GTPase-activating protein 26 isoform X1

    Related
    XP_038107126.1, XM_038251198.1
    Conserved Domains (4) summary
    cd11882
    Location:916 → 968
    SH3_GRAF-like; Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase and similar proteins
    cd01249
    Location:268 → 375
    BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
    cl02570
    Location:368 → 572
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    cl12013
    Location:22 → 228
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  3. XM_038251199.1 → XP_038107127.1  rho GTPase-activating protein 26 isoform X1

    Related
    XP_038107127.1, XM_038251199.1
    Conserved Domains (4) summary
    cd11882
    Location:916 → 968
    SH3_GRAF-like; Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase and similar proteins
    cd01249
    Location:268 → 375
    BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
    cl02570
    Location:368 → 572
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    cl12013
    Location:22 → 228
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  4. XM_038251200.1 → XP_038107128.1  rho GTPase-activating protein 26 isoform X1

    Related
    XP_038107128.1, XM_038251200.1
    Conserved Domains (4) summary
    cd11882
    Location:916 → 968
    SH3_GRAF-like; Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase and similar proteins
    cd01249
    Location:268 → 375
    BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
    cl02570
    Location:368 → 572
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    cl12013
    Location:22 → 228
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  5. XM_038251202.1 → XP_038107130.1  rho GTPase-activating protein 26 isoform X3

    Related
    XP_038107130.1, XM_038251202.1
    Conserved Domains (4) summary
    cd11882
    Location:745 → 797
    SH3_GRAF-like; Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase and similar proteins
    cd01249
    Location:97 → 204
    BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
    cl02570
    Location:197 → 401
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    cl12013
    Location:1 → 81
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
Nucleotide Protein Strain
Heading Accession and Version

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