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Lrrk Leucine-rich repeat kinase [ Culex quinquefasciatus (southern house mosquito) ]

Gene ID: 6045236, updated on 23-May-2024

Summary

Gene symbol
Lrrk
Gene description
Leucine-rich repeat kinase
See related
VectorBase:CQUJHB002334; EnsemblRapid:LOC6045236
Gene type
protein coding
RefSeq status
MODEL
Organism
Culex quinquefasciatus
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Culicinae; Culicini; Culex; Culex
Orthologs
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Genomic context

See Lrrk in Genome Data Viewer
Location:
chromosome: 1
Exon count:
14
Annotation release Status Assembly Chr Location
100 current VPISU_Cqui_1.0_pri_paternal (GCF_015732765.1) 1 NC_051861.1 (103797689..103859175)

Chromosome 1 - NC_051861.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC6049292 Neighboring gene cilia- and flagella-associated protein 299-like Neighboring gene phenoloxidase-activating factor 2 Neighboring gene mitochondrial import inner membrane translocase subunit TIM44 Neighboring gene uncharacterized LOC119765300 Neighboring gene 26S proteasome non-ATPase regulatory subunit 10 Neighboring gene DNA damage-regulated autophagy modulator protein 2

Genomic regions, transcripts, and products

Genomic Sequence:
NC_051861.1 Chromosome 1 Reference VPISU_Cqui_1.0_pri_paternal Primary Assembly

General protein information

Preferred Names
leucine-rich repeat serine/threonine-protein kinase 1
Names
V-1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Culex quinquefasciatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VPISU_Cqui_1.0_pri_paternal Primary Assembly

Genomic

  1. NC_051861.1 Reference VPISU_Cqui_1.0_pri_paternal Primary Assembly

    Range
    103797689..103859175
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038248890.1XP_038104818.1  leucine-rich repeat serine/threonine-protein kinase 1 isoform X2

    UniProtKB/TrEMBL
    B0WZ06
    Related
    XP_038104818.1, XM_038248890.1
    Conserved Domains (8) summary
    PRK15370
    Location:594726
    PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
    COG4886
    Location:590866
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:595617
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:4778
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:191276
    Ank_2; Ankyrin repeats (3 copies)
    pfam16095
    Location:13031461
    COR; C-terminal of Roc, COR, domain
    cl21453
    Location:18772171
    PKc_like; Protein Kinases, catalytic domain
    cl38936
    Location:10781284
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  2. XM_038248891.1XP_038104819.1  leucine-rich repeat serine/threonine-protein kinase 1 isoform X3

    UniProtKB/TrEMBL
    B0WZ06
    Related
    XP_038104819.1, XM_038248891.1
    Conserved Domains (8) summary
    PRK15370
    Location:586718
    PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
    COG4886
    Location:582858
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:587609
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:4778
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:191276
    Ank_2; Ankyrin repeats (3 copies)
    pfam16095
    Location:12951453
    COR; C-terminal of Roc, COR, domain
    cl21453
    Location:18692163
    PKc_like; Protein Kinases, catalytic domain
    cl38936
    Location:10701276
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  3. XM_038248888.1XP_038104816.1  leucine-rich repeat serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    B0WZ06
    Related
    XP_038104816.1, XM_038248888.1
    Conserved Domains (9) summary
    PRK15370
    Location:600732
    PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
    COG0666
    Location:119367
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    COG4886
    Location:596872
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:601623
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:5384
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:197282
    Ank_2; Ankyrin repeats (3 copies)
    pfam16095
    Location:13091467
    COR; C-terminal of Roc, COR, domain
    cl21453
    Location:18832177
    PKc_like; Protein Kinases, catalytic domain
    cl38936
    Location:10841290
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  4. XM_038248892.1XP_038104820.1  leucine-rich repeat serine/threonine-protein kinase 1 isoform X4

    UniProtKB/TrEMBL
    B0WZ06
    Related
    XP_038104820.1, XM_038248892.1
    Conserved Domains (9) summary
    PRK15370
    Location:489621
    PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
    COG0666
    Location:14232
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    COG4886
    Location:485761
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:490512
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:83114
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:86171
    Ank_2; Ankyrin repeats (3 copies)
    pfam16095
    Location:11981356
    COR; C-terminal of Roc, COR, domain
    cl21453
    Location:17722066
    PKc_like; Protein Kinases, catalytic domain
    cl38936
    Location:9731179
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  5. XM_038248893.1XP_038104821.1  leucine-rich repeat serine/threonine-protein kinase 1 isoform X5

    UniProtKB/TrEMBL
    B0WZ06
    Related
    XP_038104821.1, XM_038248893.1
    Conserved Domains (9) summary
    PRK15370
    Location:481613
    PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
    COG0666
    Location:14224
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    COG4886
    Location:477753
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:482504
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:83114
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:86171
    Ank_2; Ankyrin repeats (3 copies)
    pfam16095
    Location:11901348
    COR; C-terminal of Roc, COR, domain
    cl21453
    Location:17642058
    PKc_like; Protein Kinases, catalytic domain
    cl38936
    Location:9651171
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases