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dcun1d4 DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae) [ Danio rerio (zebrafish) ]

Gene ID: 556765, updated on 18-Sep-2024

Summary

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Official Symbol
dcun1d4provided by ZNC
Official Full Name
DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)provided by ZNC
Primary source
ZFIN:ZDB-GENE-041014-248
See related
Ensembl:ENSDARG00000092394 AllianceGenome:ZFIN:ZDB-GENE-041014-248
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
DCNL4; si:ch211-14g4.1
Summary
Predicted to enable cullin family protein binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin-like protein binding activity. Predicted to be involved in positive regulation of protein neddylation; positive regulation of ubiquitin-protein transferase activity; and protein neddylation. Predicted to be located in nucleus. Predicted to be part of ubiquitin ligase complex. Orthologous to human DCUN1D4 (defective in cullin neddylation 1 domain containing 4). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See dcun1d4 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (23203946..23226453, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (23304846..23327353, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene sarcoglycan, beta (dystrophin-associated glycoprotein) Neighboring gene leucine rich repeat containing 66 Neighboring gene U5 spliceosomal RNA Neighboring gene OCIA domain containing 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cullin family protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cullin family protein binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables ubiquitin conjugating enzyme binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin-like protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in positive regulation of protein neddylation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in protein neddylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
DCN1-like protein 4
Names
DCUN1 domain-containing protein 4
defective in cullin neddylation protein 1-like protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001032366.3 → NP_001027538.1  DCN1-like protein 4

    Status: PROVISIONAL

    Source sequence(s)
    BX323889, CT583700
    UniProtKB/Swiss-Prot
    Q5RHX6
    UniProtKB/TrEMBL
    A0A8M1N7L9, A5WW84
    Related
    ENSDARP00000114939.1, ENSDART00000142721.3
    Conserved Domains (1) summary
    pfam03556
    Location:188 → 299
    Cullin_binding; Cullin binding

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    23203946..23226453 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068215454.1 → XP_068071555.1  DCN1-like protein 4 isoform X2

  2. XM_021468427.2 → XP_021324102.1  DCN1-like protein 4 isoform X2

    UniProtKB/Swiss-Prot
    Q5RHX6
    UniProtKB/TrEMBL
    A0A8M9PBR3
    Conserved Domains (1) summary
    pfam03556
    Location:114 → 224
    Cullin_binding; Cullin binding

  3. XM_009294665.4 → XP_009292940.3  DCN1-like protein 4 isoform X1

  4. XM_021468426.2 → XP_021324101.1  DCN1-like protein 4 isoform X2

    UniProtKB/Swiss-Prot
    Q5RHX6
    UniProtKB/TrEMBL
    A0A8M9PBR3
    Conserved Domains (1) summary
    pfam03556
    Location:114 → 224
    Cullin_binding; Cullin binding

  5. XM_009294666.4 → XP_009292941.1  DCN1-like protein 4 isoform X2

    See identical proteins and their annotated locations for XP_009292941.1

    UniProtKB/Swiss-Prot
    Q5RHX6
    UniProtKB/TrEMBL
    A0A8M9PBR3
    Conserved Domains (1) summary
    pfam03556
    Location:114 → 224
    Cullin_binding; Cullin binding

  6. XM_068215455.1 → XP_068071556.1  DCN1-like protein 4 isoform X2

    Related
    ENSDARP00000120052.1, ENSDART00000144933.2
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5RHX6.2 GenPept UniProtKB/Swiss-Prot:Q5RHX6

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