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itga6l integrin, alpha 6, like [ Danio rerio (zebrafish) ]

Gene ID: 555254, updated on 27-Mar-2024

Summary

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Official Symbol
itga6lprovided by ZNC
Official Full Name
integrin, alpha 6, likeprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040914-57
See related
AllianceGenome:ZFIN:ZDB-GENE-040914-57
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:6912374; si:ch211-221c23.3
Summary
Predicted to act upstream of or within cell adhesion and integrin-mediated signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of integrin complex. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See itga6l in Genome Data Viewer
Location:
chromosome: 14
Exon count:
20
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (41530761..41552063, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (41163507..41186960, complement)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene cholinergic receptor, nicotinic, beta 5b Neighboring gene cholinergic receptor nicotinic beta 3 subunit b Neighboring gene integrin alpha-6-like Neighboring gene novel immune-type receptor 14b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The medaka novel immune-type receptor (NITR) gene clusters reveal an extraordinary degree of divergence in variable domains. Desai S, et al. BMC Evol Biol, 2008 Jun 19. PMID 18565225, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables integrin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
  
involved_in cell adhesion mediated by integrin IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell-cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell-matrix adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in integrin-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in leukocyte migration IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of integrin complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
integrin alpha-6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    41530761..41552063 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021481280.1 → XP_021336955.1  integrin alpha-6 isoform X1

    UniProtKB/TrEMBL
    A0A8M9QPM6
    Conserved Domains (3) summary
    smart00191
    Location:115 → 159
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam08441
    Location:209 → 672
    Integrin_alpha2; Integrin alpha
    pfam13517
    Location:127 → 197
    VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394928.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    3372..9236 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021472895.1 → XP_021328570.1  integrin alpha-6 isoform X2

    UniProtKB/TrEMBL
    A0A8M9Q5D4
    Conserved Domains (1) summary
    pfam08441
    Location:25 → 488
    Integrin_alpha2; Integrin alpha
Nucleotide Protein Strain
Heading Accession and Version

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