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rnd1b Rho family GTPase 1b [ Danio rerio (zebrafish) ]

Gene ID: 553414, updated on 12-Sep-2024

Summary

Official Symbol
rnd1bprovided by ZNC
Official Full Name
Rho family GTPase 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060315-7
See related
Ensembl:ENSDARG00000004218 AllianceGenome:ZFIN:ZDB-GENE-060315-7
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
rnd1a; rnd1l; wu:fk50c04; zgc:153089
Summary
Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including cytoskeleton organization; regulation of actin cytoskeleton organization; and regulation of cell shape. Predicted to act upstream of or within small GTPase mediated signal transduction. Predicted to be active in several cellular components, including cell cortex; cytoplasmic vesicle; and cytoskeleton. Is expressed in several structures, including blastomere; germ ring; margin; optic primordium; and presumptive mesoderm. Orthologous to human RND1 (Rho family GTPase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 23
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (26979171..27006062)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (27052630..27079521)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene dentin sialophosphoprotein-like Neighboring gene calcium channel, voltage-dependent, beta 3b Neighboring gene deltex E3 ubiquitin ligase 3 Neighboring gene prostaglandin E synthase 3a (cytosolic)

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in actin filament organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell migration IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Rho family GTPase 1b
Names
Rho family GTPase 1 like
ras-like protein Rnd1a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001044396.2NP_001037861.1  Rho family GTPase 1b

    See identical proteins and their annotated locations for NP_001037861.1

    Status: VALIDATED

    Source sequence(s)
    BC122138, CU862020
    UniProtKB/TrEMBL
    B2GRK0, F6P7L7, Q52WX7
    Related
    ENSDARP00000022232.6, ENSDART00000018654.9
    Conserved Domains (1) summary
    cd04174
    Location:1232
    Rnd1_Rho6; Rnd1/Rho6 GTPases

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    26979171..27006062
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395154.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    222246..246248
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)