ctu2 cytosolic thiouridylase subunit 2 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: ctu2provided by Xenbase
Official Full Name: cytosolic thiouridylase subunit 2provided by Xenbase
Primary source: Xenbase:XB-GENE-5732028
See related: Ensembl:ENSXETG00000011252
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: ncs2; ctu2-a; ctu2-b; upf0432
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	4	NC_030680.2 (58181676..58197467)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	4	NC_030680.1 (60699439..60718247)

Chromosome 4 - NC_030680.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables nucleotidyltransferase activity	IEA Inferred from Electronic Annotation more info
enables sulfurtransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables tRNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein urmylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tRNA processing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tRNA thio-modification	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tRNA thio-modification	ISS Inferred from Sequence or Structural Similarity more info
involved_in tRNA wobble position uridine thiolation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within tRNA wobble uridine modification	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tRNA wobble uridine modification	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: cytoplasmic tRNA 2-thiolation protein 2

Names: cytosolic thiouridylase subunit 2 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001039740.1 → NP_001034829.1 cytoplasmic tRNA 2-thiolation protein 2

See identical proteins and their annotated locations for NP_001034829.1

Status: PROVISIONAL

Source sequence(s)

CR762362

UniProtKB/Swiss-Prot

B3DL40, Q28ES8, Q5FVY8

UniProtKB/TrEMBL

A0A4X2Q847

Conserved Domains (2) summary

pfam10288
Location:343 → 471

CTU2; Cytoplasmic tRNA 2-thiolation protein 2

cl00292
Location:47 → 147

AANH_like; Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide.

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

Range

58181676..58197467

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_012961023.2 → XP_012816477.2 cytoplasmic tRNA 2-thiolation protein 2 isoform X1

UniProtKB/Swiss-Prot

B3DL40, Q28ES8, Q5FVY8

UniProtKB/TrEMBL

A0A4X2Q847

Related

ENSXETP00000024569.4, ENSXETT00000024569.4

Conserved Domains (2) summary

pfam10288
Location:343 → 471

CTU2; Cytoplasmic tRNA 2-thiolation protein 2

cl00292
Location:47 → 147

AANH_like; Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide.
XM_031900062.1 → XP_031755922.1 cytoplasmic tRNA 2-thiolation protein 2 isoform X2

UniProtKB/TrEMBL

A0A4X2Q847, A0A8J1JDG3

Conserved Domains (2) summary

pfam10288
Location:343 → 471

CTU2; Cytoplasmic tRNA 2-thiolation protein 2

cl00292
Location:47 → 147

AANH_like; Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide.